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    Article

    Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells

    Notch-1 inhibits apoptosis in some transformed cells through incompletely understood mechanisms. Notch-1 can increase nuclear factor-kappa B (NF-κB) activity through a variety of mechanisms. Overexpression of ...

    L L Song, Y Peng, J Yun, P Rizzo, V Chaturvedi, S Weijzen, W M Kast… in Oncogene (2008)

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    Chapter

    Vaccination Strategies to Induce T-Cell Immunity Against Tumours

    Effector T cells recognize immunogenic peptides that are presented on the cell membrane in the context of major histocompatibility complex (MHC) molecules. The vast majority of T cells consists of either CD8+ ...

    M. E. Ressing, R. E. M. Toes… in Cytokines and Growth Factors in Blood Tran… (1997)

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    Chapter

    The Promise of T Cell Immunotherapy of Cancer

    The prospects for immunotherapy of cancer have fluctuated considerably since the beginning of this century when Paul Ehrlich first proposed that the immune system might be of prime importance in protection aga...

    C. J. M. Melief, W. M. Kast in Advances in haemapheresis (1991)