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Article
Notch-1 associates with IKKα and regulates IKK activity in cervical cancer cells
Notch-1 inhibits apoptosis in some transformed cells through incompletely understood mechanisms. Notch-1 can increase nuclear factor-kappa B (NF-κB) activity through a variety of mechanisms. Overexpression of ...
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Article
Differences in the effectiveness of delivery of B- and CTL-epitopes incorporated into the Hepatitis B core antigen (HBcAg) c/e1-region
Work from a number of laboratories including our own has shown that foreign B-epitopes inserted into the c/e1-region of Hepatitis B core antigen (HBcAg) elicit powerful antibody responses when mice are immunis...
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Chapter
Vaccination Strategies to Induce T-Cell Immunity Against Tumours
Effector T cells recognize immunogenic peptides that are presented on the cell membrane in the context of major histocompatibility complex (MHC) molecules. The vast majority of T cells consists of either CD8+ ...
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Chapter
The Promise of T Cell Immunotherapy of Cancer
The prospects for immunotherapy of cancer have fluctuated considerably since the beginning of this century when Paul Ehrlich first proposed that the immune system might be of prime importance in protection aga...
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Chapter and Conference Paper
Peroxidases
A brief description is made of properties of a wide variety of peroxidases which illustrates differences as well as similarities. The article begins with monoheme enzymes and ends with myeloperoxidase and Pseu...
