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Article
Pure tissue repairs: a timely and critical revival
“The majority of hernias can be satisfactorily repaired by using the tissues at hand. The use of mesh prosthesis should be restricted to those few hernias in which tension or lack of good fascial structures pr...
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Article
Open AccessMap** genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma
Almost all genomic studies of breast cancer have focused on well-established tumours because it is technically challenging to study the earliest mutational events occurring in human breast epithelial cells. To...
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Article
In vivo polypropylene mesh degradation is hardly a myth
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Article
Safety considerations for synthetic sling surgery
The effectiveness of synthetic midurethral slings (SMUS) is comparable to the time-honoured gold standards—the autologous fascial sling and Burch colposuspensi...
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Article
Open AccessImmunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis
The pathogenesis of pancreatic ductal adenocarcinoma (PDAC) involves multi-stage development of molecular aberrations affecting signaling pathways that regulate cancer growth and progression. This study was pe...
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Article
Open AccessQuantitative image analysis of immunohistochemical stains using a CMYK color model
Computer image analysis techniques have decreased effects of observer biases, and increased the sensitivity and the throughput of immunohistochemistry (IHC) as a tissue-based procedure for the evaluation of di...
