15 Result(s)
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Article
NK cell activation and tumor infiltration are involved in the antitumor mechanism of Virulizin
Previous studies have demonstrated antitumor efficacy of Virulizin in several human tumor xenograft models and a critical role for macrophages in the antitumor mechanism of Virulizin. Although there is growing...
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Article
Virulizin, a novel immunotherapy agent, activates NK cells through induction of IL-12 expression in macrophages
Virulizin, a novel biological response modifier, has demonstrated significant antitumor efficacy in a variety of human tumor xenograft models including melanoma, pancreatic cancer, breast cancer, ovarian cance...
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Article
Virulizin® induces production of IL-17E to enhance antitumor activity by recruitment of eosinophils into tumors
Virulizin® has demonstrated strong antitumor efficacy in a variety of human tumor xenograft models including melanoma, pancreatic cancer, breast cancer, ovarian cancer and prostate cancer. Our previous studies ha...
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Article
Open AccessRisk factors for human infection with West Nile Virus in Connecticut: a multi-year analysis
The optimal method for early prediction of human West Nile virus (WNV) infection risk remains controversial. We analyzed the predictive utility of risk factor data for human WNV over a six-year period in Conne...
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Article
IL-17E, a proinflammatory cytokine, has antitumor efficacy against several tumor types in vivo
Interleukin-17E (IL-17E) belongs to a novel family of cytokines that possess significant homology to IL-17. IL-17E has potent inflammatory effects in vitro and in vivo. Overexpression of IL-17E in mice results...
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Article
Open AccessThe emergency to home project: impact of an emergency department care coordinator on hospital admission and emergency department utilization among seniors
Seniors comprise 14% to 21% of all emergency department (ED) visits, yet are disproportionately larger users of ED and inpatient resources. ED care coordinators (EDCCs) target seniors at risk for functional de...
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Chapter
Molecular Pathology of Pediatric Oculoplastic Disorders
The landscape of diagnostic pathology has changed tremendously over the last few decades. New technology and improvement on classic techniques have allowed pathologists to probe deeper into the molecular mecha...
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Article
Open AccessDeep learning networks find unique mammographic differences in previous negative mammograms between interval and screen-detected cancers: a case-case study
To determine if mammographic features from deep learning networks can be applied in breast cancer to identify groups at interval invasive cancer risk due to masking beyond using traditional breast density meas...
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Living Reference Work Entry In depth
Pathology of the Eyelids
The eyelid is a complex structure, composed of skin, orbicularis muscle, tarsus, and conjunctiva. Bordered by the eyebrow superiorly and cheek inferiorly, the eyelids are split into an upper and lower eyelids....
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Article
Awareness campaigns of atrial fibrillation as an opportunity for early detection by pharmacists: an international cross-sectional study
Atrial fibrillation (AF) accounts for up to one third of strokes, one of the lead mortality causes worldwide. The European Society of Cardiology guidelines recommend opportunistic screening as a means to incre...
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Article
The WISDOM study: a new approach to screening can and should be tested
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Reference Work Entry In depth
Pathology of the Eyelids
The eyelid is a complex structure, composed of skin, orbicularis muscle, tarsus, and conjunctiva. Bordered by the eyebrow superiorly and cheek inferiorly, the eyelids are split into an upper and lower eyelids....
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Article
Patient perspectives on window of opportunity clinical trials in early-stage breast cancer
Window of opportunity trials (WOT) are increasingly common in oncology research. In WOT participants receive a drug between diagnosis and anti-cancer treatment, usually for the purpose of investigating that dr...
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Article
Open AccessImpact of Bacteria Types on the Clinical Outcomes of Spontaneous Bacterial Peritonitis
Cirrhotic patients presenting with spontaneous bacterial peritonitis (SBP) have elevated risk of short-term mortality. While high Model for End-Stage Liver Disease-Sodium score (MELD-Na) and ascites culture yi...
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Article
Open AccessUtility of a virtual small group cognitive behaviour program for autistic children during the pandemic: evidence from a community-based implementation study
Autistic children often experience socioemotional difficulties relating to emotion regulation and mental health problems. Supports for autistic children involve the use of adapted interventions that target emo...
