6 Result(s)
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Article
The biliary tree—a reservoir of multipotent stem cells
This Perspectives describes the characteristics of stem and progenitor cells in the liver, biliary tree and pancreas. A hypothetical model of maturational cell lineages is presented, highlighting the common em...
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Chapter
Molecular Profiling
Molecular studies concerning cholangiocarcinoma (CCA) or gallbladder cancer are only at the beginning, and the epidemiologic, biologic, and pathological heterogeneity of these cancers constitutes a challeng...
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Article
Open AccessTransplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis
Efforts to identify cell sources and approaches for cell therapy of liver diseases are ongoing, taking into consideration the limits recognized for adult liver tissue and for other forms of stem cells. In the ...
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Article
Open AccessCholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Cholangiocarcinomas are a heterogeneous group of bile duct cancers and the second most common primary liver tumour worldwide. In this Consensus statement, the newly formed European Network for the Study of Cho...
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Article
Open AccessCholangiocarcinoma 2020: the next horizon in mechanisms and management
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant tumours that can arise at any point of the biliary tree. Their incidence is increasing globally, currently accounting for ~...
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Article
Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance
Cholangiocarcinoma (CCA) is a rare malignancy that develops at any point along the biliary tree. CCA has a poor prognosis, its clinical management remains challenging, and effective treatments are lacking. The...
