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  1. Article

    Open Access

    Downregulation of the Rho GTPase pathway abrogates resistance to ionizing radiation in wild-type p53 glioblastoma by suppressing DNA repair mechanisms

    Glioblastoma (GBM), the most common aggressive brain tumor, is characterized by rapid cellular infiltration and is routinely treated with ionizing radiation (IR), but therapeutic resistance inevitably recurs. ...

    Yuli Thamires Magalhaes, Viktor Kalbermatter Boell in Cell Death & Disease (2023)