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Article
HiRIEF LC-MS enables deep proteome coverage and unbiased proteogenomics
High-resolution isoelectric focusing (HiRIEF) of peptides followed by mass spectrometry analysis, combined with accurate peptide pI prediction, allows a reduction of protein database search space, enabling dee...
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Article
Open AccessA cross-validation scheme for machine learning algorithms in shotgun proteomics
Peptides are routinely identified from mass spectrometry-based proteomics experiments by matching observed spectra to peptides derived from protein databases. The error rates of these identifications can be es...