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    Article

    HiRIEF LC-MS enables deep proteome coverage and unbiased proteogenomics

    High-resolution isoelectric focusing (HiRIEF) of peptides followed by mass spectrometry analysis, combined with accurate peptide pI prediction, allows a reduction of protein database search space, enabling dee...

    Rui M M Branca, Lukas M Orre, Henrik J Johansson, Viktor Granholm in Nature Methods (2014)

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    Open Access

    A cross-validation scheme for machine learning algorithms in shotgun proteomics

    Peptides are routinely identified from mass spectrometry-based proteomics experiments by matching observed spectra to peptides derived from protein databases. The error rates of these identifications can be es...

    Viktor Granholm, William Stafford Noble, Lukas Käll in BMC Bioinformatics (2012)