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Open AccessrAAV-compatible MiniPromoters for restricted expression in the brain and eye
Small promoters that recapitulate endogenous gene expression patterns are important for basic, preclinical, and now clinical research. Recently, there has been a promising revival of gene therapy for diseases ...
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Open AccessIdentification of a set of genes showing regionally enriched expression in the mouse brain
The Pleiades Promoter Project aims to improve gene therapy by designing human mini-promoters (< 4 kb) that drive gene expression in specific brain regions or cell-types of therapeutic interest. Our goal was to...
