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    Article

    Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

    Programmed death (apoptosis) is turned on in damaged or unwanted cells to secure their clean and safe self-elimination. The initial apoptotic events are coordinated in mitochondria, whereby several proapoptoti...

    Valerian E Kagan, Vladimir A Tyurin, Jianfei Jiang in Nature Chemical Biology (2005)

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    Cytochrome c release is required for phosphatidylserine peroxidation during fas-triggered apoptosis in lung epithelial A549 cells

    Oxidation of phosphatidylserine (PtdSer) has been shown to play a pivotal role in signaling during cell apoptosis and subsequent recognition of apoptotic cells by phagocytes. However, the redox catalytic mecha...

    Jianfei Jiang, Vidisha Kini, Natalia Belikova, Behice F. Serinkan in Lipids (2004)