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Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors
Programmed death (apoptosis) is turned on in damaged or unwanted cells to secure their clean and safe self-elimination. The initial apoptotic events are coordinated in mitochondria, whereby several proapoptoti...
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Article
Cytochrome c release is required for phosphatidylserine peroxidation during fas-triggered apoptosis in lung epithelial A549 cells
Oxidation of phosphatidylserine (PtdSer) has been shown to play a pivotal role in signaling during cell apoptosis and subsequent recognition of apoptotic cells by phagocytes. However, the redox catalytic mecha...