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    Article

    Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy

    The hippocampus is the most common seizure focus in people. In the hippocampus, aberrant neurogenesis plays a critical role in the initiation and progression of epilepsy in rodent models, but it is unknown whe...

    Aswathy Ammothumkandy, Kristine Ravina, Victoria Wolseley in Nature Neuroscience (2022)

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    Open Access

    Robust RNA-Seq of aRNA-amplified single cell material collected by patch clamp

    Most single cell RNA sequencing protocols start with single cells dispersed from intact tissue. High-throughput processing of the separated cells is enabled using microfluidics platforms. However, dissociation...

    Jae Mun “Hugo” Kim, Adrian Camarena, Christopher Walker, Ming Yi Lin in Scientific Reports (2020)

  3. Article

    Open Access

    Zika Virus Infects Intermediate Progenitor Cells and Post-mitotic Committed Neurons in Human Fetal Brain Tissues

    Zika virus (ZIKV) infection is associated with microcephaly in fetuses, but the pathogenesis of ZIKV-related microcephaly is not well understood. Here we show that ZIKV infects the subventricular zone in human...

    Ming-Yi Lin, Yi-Ling Wang, Wan-Lin Wu, Victoria Wolseley in Scientific Reports (2017)