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    Open Access

    Pharmacokinetics and Tolerability of Zibotentan in Patients with Concurrent Moderate Renal and Moderate Hepatic Impairment

    Zibotentan, a selective endothelin A receptor antagonist, is in development for chronic liver and kidney disease. The pharmacokinetics (PK) of zibotentan were previously investigated in patients with either re...

    Anne-Kristina Mercier, Mikael Sunnåker, Sebastian Ueckert… in Clinical Pharmacokinetics (2023)

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