Page
%P
2 Result(s)
within
Anne-Kristina Mercier
-
Article
Open AccessLong-term safety of brazikumab in the open-label period of a randomized phase 2a study of patients with Crohn’s disease
Short-term efficacy and safety of brazikumab (MEDI2070), a human monoclonal antibody and anti-p19 subunit inhibitor of interleukin-23, was demonstrated in a phase 2a trial in patients with moderate-to-severe a...
-
Article
Open AccessPharmacokinetics and Tolerability of Zibotentan in Patients with Concurrent Moderate Renal and Moderate Hepatic Impairment
Zibotentan, a selective endothelin A receptor antagonist, is in development for chronic liver and kidney disease. The pharmacokinetics (PK) of zibotentan were previously investigated in patients with either re...
