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  1. Article

    Open Access

    The epicardial delivery of cardiosphere derived cells or their extracellular vesicles is safe but of limited value in experimental infarction

    The epicardial administration of therapeutics via the pericardial sac offers an attractive route, since it is minimally invasive and carries no risks of coronary embolization. The aim of this study was to asse...

    Verónica Crisóstomo, Claudia Baéz-Diaz, Virginia Blanco-Blázquez in Scientific Reports (2021)

  2. Article

    Author Correction: The Intrapericardial Delivery of Extracellular Vesicles from Cardiosphere-Derived Cells Stimulates M2 Polarization during the Acute Phase of Porcine Myocardial Infarction

    The original version of this article unfortunately contained a mistake. In the author group, the correct family name of Dr. Rebeca is “Blázquez” and the correct family name of Dr. Francisco Miguel is “Sánchez-...

    Esther López, Rebeca Blázquez, Federica Marinaro in Stem Cell Reviews and Reports (2020)

  3. Article

    Open Access

    The Intrapericardial Delivery of Extracellular Vesicles from Cardiosphere-Derived Cells Stimulates M2 Polarization during the Acute Phase of Porcine Myocardial Infarction

    Acute myocardial infarction triggers a strong inflammatory response in the affected cardiac tissue. New therapeutic tools based on stem cell therapy may modulate the unbalanced inflammation in the damaged card...

    Esther López, Rebeca Blázquez, Federica Marinaro in Stem Cell Reviews and Reports (2020)

  4. Article

    Open Access

    Microencapsulated Insulin-Like Growth Factor-1 therapy improves cardiac function and reduces fibrosis in a porcine acute myocardial infarction model

    Insulin-like growth factor-1 (IGF-1) has demonstrated beneficial effects after myocardial infarction (MI). Microencapsulation of IGF-1 could potentially improve results. We aimed to test the effect of an intra...

    Claudia Báez-Díaz, Virginia Blanco-Blázquez in Scientific Reports (2020)

  5. Article

    Open Access

    CIBER-CLAP (CIBERCV Cardioprotection Large Animal Platform): A multicenter preclinical network for testing reproducibility in cardiovascular interventions

    Despite many cardioprotective interventions have shown to protect the heart against ischemia/reperfusion injury in the experimental setting, only few of them have succeeded in translating their findings into p...

    Xavier Rossello, Antonio Rodriguez-Sinovas, Gemma Vilahur in Scientific Reports (2019)

  6. Article

    Open Access

    Identification of very early inflammatory markers in a porcine myocardial infarction model

    Acute myocardial infarction (AMI) is one of the most deleterious conditions leading to cardiovascular diseases and mortality. The importance of an early and accurate diagnosis assures immediate medical treatme...

    Esther López, Francisco Miguel Sánchez-Margallo in BMC Veterinary Research (2019)

  7. Article

    Open Access

    Combined administration of mesenchymal stem cells overexpressing IGF-1 and HGF enhances neovascularization but moderately improves cardiac regeneration in a porcine model

    Insulin-like growth factor 1 (IGF-1) and hepatocyte growth factor (HGF) are among the most promising growth factors for promoting cardiorepair. Here, we evaluated the combination of cell- and gene-based therap...

    Guadalupe Gómez-Mauricio, Isabel Moscoso in Stem Cell Research & Therapy (2016)

  8. No Access

    Article

    Prostatic Artery Embolization (PAE) for Symptomatic Benign Prostatic Hyperplasia (BPH): Part 2, Insights into the Technical Rationale

    Rationale of prostatic artery embolization (PAE) in the treatment of symptomatic benign prostatic hyperplasia is conventionally believed to include two parts: shrinkage of the enlarged prostate gland as a resu...

    Fei Sun, Verónica Crisóstomo in CardioVascular and Interventional Radiology (2016)

  9. No Access

    Article

    Prostatic Artery Embolization (PAE) for Symptomatic Benign Prostatic Hyperplasia (BPH): Part 1, Pathological Background and Clinical Implications

    Pathological features of benign prostatic hyperplasia (BPH) dictate various responses to prostatic artery embolization (PAE). Typically, BPH originates in the transition zone and periurethral region, where sho...

    Fei Sun, Verónica Crisóstomo in CardioVascular and Interventional Radiology (2016)

  10. Article

    Open Access

    Comparison of two preclinical myocardial infarct models: coronary coil deployment versus surgical ligation

    Despite recent advances, myocardial infarction (MI) remains the leading cause of death worldwide. Pre-clinical animal models that closely mimic human MI are pivotal for a quick translation of research and swin...

    Carolina Gálvez-Montón, Cristina Prat-Vidal in Journal of Translational Medicine (2014)

  11. No Access

    Article

    Evaluation of the Effects of Temporary Covered Nitinol Stent Placement in the Prostatic Urethra: Short-Term Study in the Canine Model

    To evaluate the effect of temporary stent placement on the canine prostatic urethra.

    Verónica Crisóstomo, Ho Young Song in CardioVascular and Interventional Radiology (2007)

  12. No Access

    Article

    Fine-needle percutaneous transhepatic parenchymal portal venography by using carbon dioxide: a pilot study in pigs

    Our purpose was to evaluate the feasibility and safety of carbon dioxide (CO2) in fine-needle percutaneous transhepatic parenchymal portal venography and its potential clinical applications. Three Belgian landra...

    Fei Sun, Javier Hernández, Verónica Crisóstomo, Luis-Fernando Pineda in European Radiology (2003)

  13. No Access

    Article

    End-to-end Anastomosis in Growing Vessels Using a Novel Suturing Technique: VCS Metallic Staples

    For pediatric transplants, a suturing technique is needed that allows the vessel to grow along with better healing of the anastomosis, through eliminating exogenous and thrombogenic material in the intimal sid...

    María Carmen Calles, Marco A. Lima, Verónica Crisóstomo in Annals of Vascular Surgery (2002)