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Article
Open AccessDirect Estimation of Parameters in ODE Models Using WENDy: Weak-Form Estimation of Nonlinear Dynamics
We introduce the Weak-form Estimation of Nonlinear Dynamics (WENDy) method for estimating model parameters for non-linear systems of ODEs. Without relying on any numerical differential equation solvers, WENDy ...
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Article
Viral transmission and infection prevalence in a cannibalistic host–pathogen system
Cannibalism, while prevalent in the natural world, is often viewed as detrimental to a cannibal’s health, especially when they consume pathogen-infected conspecifics. The argument stems from the idea that cann...
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Living Reference Work Entry In depth
MONOPOLI: A Customizable Model for Forecasting COVID-19 Around the World Using Alternative Nonpharmaceutical Intervention Policy Scenarios, Human Movement Data, and Regional Demographics
During the global COVID-19 pandemic, policy makers, public health practitioners, medical experts, and laypersons have sought data that would enable evidence-based decisions about which interventions would be m...
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Article
A note on species richness and the variance of epidemic severity
The commonly observed negative correlation between the number of species in an ecological community and disease risk, typically referred to as “the dilution effect”, has received a substantial amount of attent...
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Article
Open AccessTracking U.S. Pertussis Incidence: Correlation of Public Health Surveillance and Google Search Data Varies by State
The Morbidity and Mortality Weekly Reports of the U.S. Centers for Disease Control and Prevention document a raw proxy for counts of pertussis cases in the U.S., and the Project Tycho (PT) database provides an...
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Article
Bayesian-based survival analysis: inferring time to death in host-pathogen interactions
The standard approach to modeling survival times, or more generally, time to event data, is often based on parametric assumptions that may not fit the data collected well. One of the goals of this article is t...
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Article
Combining principal component analysis with parameter line-searches to improve the efficacy of Metropolis–Hastings MCMC
When Markov chain Monte Carlo (MCMC) algorithms are used with complex mechanistic models, convergence times are often severely compromised by poor mixing rates and a lack of computational power. Methods such a...
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Article
Open AccessResearch on Emissions, Air quality, Climate, and Cooking Technologies in Northern Ghana (REACCTING): study rationale and protocol
Cooking over open fires using solid fuels is both common practice throughout much of the world and widely recognized to contribute to human health, environmental, and social problems. The public health burden ...
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Article
Erratum to: The Role of Weather in Meningitis Outbreaks in Navrongo, Ghana: A Generalized Additive Modeling Approach
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Article
The Role of Weather in Meningitis Outbreaks in Navrongo, Ghana: A Generalized Additive Modeling Approach
Bacterial (meningococcal) meningitis is a devastating infectious disease with outbreaks occurring annually during the dry season in locations within the ‘Meningitis Belt’, a region in sub-Saharan Africa stretc...
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Article
Hazard of recurrence and adjuvant treatment effects over time in lymph node-negative breast cancer
Background For patients with axillary lymph node-negative breast cancer, benefits from adjuvant therapy are smaller than in node-positive disease and thus more selective use is warranted, prompting development of...
