3 Result(s)
within
Van S Tompkins
English
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Article
Open AccessCDKN1A and FANCD2 are potential oncotargets in Burkitt lymphoma and multiple myeloma
Comparative genetic and biological studies on malignant tumor counterparts in human beings and laboratory mice may be powerful gene discovery tools for blood cancers, including neoplasms of mature B-lymphocyte...
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Article
Preclinical validation of interleukin 6 as a therapeutic target in multiple myeloma
Studies on the biologic and molecular genetic underpinnings of multiple myeloma (MM) have identified the pleiotropic, pro-inflammatory cytokine, interleukin-6 (IL-6), as a factor crucial to the growth, prolife...
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Article
Open AccessNF-κB/STAT3/PI3K signaling crosstalk in iMycEμ B lymphoma
Myc is a well known driver of lymphomagenesis, and Myc-activating chromosomal translocation is the recognized hallmark of Burkitt lymphoma, an aggressive form of non-Hodgkin's lymphoma. We developed a model th...
