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Article
Microtubule lattice spacing governs cohesive envelope formation of tau family proteins
Tau is an intrinsically disordered microtubule-associated protein (MAP) implicated in neurodegenerative disease. On microtubules, tau molecules segregate into two kinetically distinct phases, consisting of eit...
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Article
Open AccessAnillin propels myosin-independent constriction of actin rings
Constriction of the cytokinetic ring, a circular structure of actin filaments, is an essential step during cell division. Mechanical forces driving the constriction are attributed to myosin motor proteins, whi...
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Article
Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes
Tau is an intrinsically disordered protein, which diffuses on microtubules1. In neurodegenerative diseases, collectively termed tauopathies, malfunction of tau and its detachment from axonal microtubules are corr...