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Article
Open AccessHealth care professionals’ experiences of dealing with cancer cachexia
Cancer cachexia (CC) is a debilitating syndrome severely impacting patients’ quality of life and survivorship. We aimed to investigate the health care professionals’ (HCPs’) experiences of dealing with CC.
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Article
Open AccessChronic treatment of curcumin improves hepatic lipid metabolism and alleviates the renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats
Chronic kidney disease (CKD), including nephrotic syndrome, is a major cause of cardiovascular morbidity and mortality. The literature indicates that CKD is associated with profound lipid disorders due to the ...
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Article
Open AccessSynergistic study of a Danshen (Salvia Miltiorrhizae Radix et Rhizoma) and Sanqi (Notoginseng Radix et Rhizoma) combination on cell survival in EA.hy926 cells
This study investigated the protective effects of the Danshen (DS) and Sanqi (SQ) herb pair on cell survival in the human cardiovascular endothelial (EA.hy926) cell line exposed to injury.
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Reference Work Entry In depth
Cachexia/Anorexia and Feeding Difficulties
Symptoms related to anorexia (loss of appetite), cachexia (muscle loss and wasting) and dysphagia (reduced ability to eat) are devastating for a person with a palliative illness and their families. They are co...
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Article
Open AccessAnalysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects
The optimal health benefits of curcumin are limited by its low solubility in water and corresponding poor intestinal absorption. Cyclodextrins (CD) can form inclusion complexes on a molecular basis with lipoph...
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Article
Open Access(R)-α-Lipoic acid inhibits fructose-induced myoglobin fructation and the formation of advanced glycation end products (AGEs) in vitro
Fructose-mediated protein glycation (fructation) has been linked to an increase in diabetic and cardiovascular complications due to over consumption of high-fructose containing diets in recent times. The objec...
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Living Reference Work Entry In depth
Cachexia/Anorexia and Feeding Difficulties
Symptoms related to anorexia (loss of appetite), cachexia (muscle loss and wasting) and dysphagia (reduced ability to eat) are devastating for a person with a palliative illness and their families. They are co...
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Article
Open AccessA multivariate analysis on the comparison of raw notoginseng (Sanqi) and its granule products by thin-layer chromatography and ultra-performance liquid chromatography
Granule products produced from medicinal herbs are gaining popularity. However, there have been few studies comparing the quality or efficacy of granules with those of herbal formulations. This study aims to c...
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Chapter
Herbal Medicines for the Management of Diabetes
Herbal medicines have been used in the management of diabetes in traditional medicine. This chapter reviews recent findings of the most popular herbs reported to treat diabetes through their relevant mechanist...
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Article
Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway
Nuclear factor (NF)-κB is important in the generation of inflammation. Besides regulating lipid metabolism, peroxisome proliferator-activated receptor (PPAR)-α activators also reduce NF-κB activation to termin...
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Article
Open AccessThe pathophysiological function of peroxisome proliferator-activated receptor-γ in lung-related diseases
Research into respiratory diseases has reached a critical stage and the introduction of novel therapies is essential in combating these debilitating conditions. With the discovery of the peroxisome proliferato...
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Article
Chemistry and Pharmacology of Gynostemma pentaphyllum
In traditional Chinese medicine, Gynostemma pentaphyllum (Thunb.) Makino is a herbal drug of extreme versatility and has been extensively researched in China. The dammarane saponins isolated from Gynostemma penta...