-
Article
Open AccessA cost-effectiveness analysis of an integrated clinical-radiogenomic screening program for the identification of BRCA 1/2 carriers (e-PROBE study)
Current approach to identify BRCA 1/2 carriers in the general population is ineffective as most of the carriers remain undiagnosed. Radiomics is an emerging tool for large scale quantitative analysis of featur...
-
Chapter
Brachytherapy for Nose Vestibule Malignancies: Functional Results
Nasal cavity is part of the respiratory system with multiple delicate functions, which can be compromised by different pathological conditions and also as a result of treatments. Surgical treatment of nose ves...
-
Article
Stereotactic radiosurgery for bone metastases in oligometastatic prostate cancer patients: DESTROY-2 clinical trial subanalysis
Aim of this analysis was to report toxicity and clinical outcomes in oligorecurrent prostate cancer (PCa) patients treated with single fraction stereotactic radiosurgery (SRS) for bone metastases.
-
Article
Stereotactic body radiotherapy to lymph nodes in oligoprogressive castration-resistant prostate cancer patients: a post hoc analysis from two phase I clinical trials
The prognosis of prostate cancer (PC) is generally favorable but the incidence of metastases is relatively high after the treatment of the primary tumor, especially in high-risk patients. Fractionated stereota...
-
Article
Preoperative chemoradiotherapy affects postoperative outcomes and functional results in patients treated with transanal endoscopic microsurgery for rectal neoplasms
The aim of this study was to quantify the incidence of short-term postoperative complications and functional disorders at 1 year from transanal endoscopic microsurgery (TEM) for rectal neoplasms, to compare pa...
-
Article
Open AccessRecent advances in (chemo-)radiation therapy for rectal cancer: a comprehensive review
The role of radiation therapy in the treatment of (colo)-rectal cancer has changed dramatically over the past decades. Introduced with the aim of reducing the high rates of local recurrences after conventional...
-
Chapter
Microvascular Techniques
Reconstructive microsurgery has become an integral part of head and neck reconstructive surgery, allowing the completion of complex resections with predictable outcome. These improvements are related to techno...
-
Article
Open AccessMR-guidance in clinical reality: current treatment challenges and future perspectives
Magnetic Resonance-guided radiotherapy (MRgRT) marks the beginning of a new era. MR is a versatile and suitable imaging modality for radiotherapy, as it enables direct visualization of the tumor and the surrou...
-
Article
IMproved MAnagement (IM-MA study) in cancer-related pain: the value of a joint approach by an integrated team of radiotherapist and anesthetist
Purpose of this study was to retrospectively review our experience of multidisciplinary clinic providing a joint approach by radiation oncologist and anesthetist for patients with cancer pain to evaluate the a...
-
Article
Multidisciplinary team in head and neck cancer: a management model
Nowadays, the multidisciplinary team (MDT) is an essential component for oncologic disease management. Its benefit is also extensively recognized in head and neck cancer (HNC) community, due to tumor rarity an...
-
Article
The PRICE study: The role of conventional and diffusion-weighted magnetic resonance imaging in assessment of locally advanced cervical cancer patients administered by chemoradiation followed by radical surgery
To analyse the role of DW-MRI in early prediction of pathologically-assessed residual disease in locally-advanced cervical cancer (LACC) treated with neoadjuvant chemoradiotherapy followed by radical surgery.
-
Article
Authors’ reply to “Rectal sparing approach after preoperative radio- and/or chemotherapy (RESARCH) in patients with rectal cancer: potential pitfalls of a multicentre observational study”
-
Chapter
What Is the Ongoing Recommendation in the Management of Rectal Cancer?
During the past 20 years, we have seen major changes in the way patients with rectal cancer are investigated and treated. The key components are the improvements in preoperative staging, in surgical technique ...
-
Article
Role of Inflammatory Diseases in Hypertension
Chronic inflammatory diseases (CID) are characterized by an increased risk of cardiovascular (CV) morbidity and mortality. Several mechanisms, including early acceleration of subclinical atherosclerotic damage...
-
Article
Rectal sparing approach after preoperative radio- and/or chemotherapy (RESARCH) in patients with rectal cancer: a multicentre observational study
Rectum-sparing approaches appear to be appropriate in rectal cancer patients with a major (mCR) or complete clinical response (cCR) after neoadjuvant therapy. The aim of the present study is to evaluate the e...
-
Article
Infrared absorption of fs-laser textured CVD diamond
Nanoscale periodic texturing on polycrystalline CVD diamond surface was performed to obtain a significant increase in optical absorptance to visible and near-infrared radiation. Surface texturing, obtained by...
-
Article
Open AccessOptical properties of femtosecond laser-treated diamond
A laser-induced periodic surface structure (LIPSS) has been fabricated on polycrystalline diamond by an ultrashort Ti:Sapphire pulsed laser source (λ = 800 nm, P = 3 mJ, 100 fs) in a high vacuum chamber (<10−7 mb...
-
Article
Raman investigation of femtosecond laser-induced graphitic columns in single-crystal diamond
We report on the fabrication of graphitic columns induced in single-crystal diamond plates using 100 fs laser pulses at 800 nm wavelength. Different values of laser fluence (0.6–1.2 J/cm2) and graphitization spee...
-
Article
Low-dose fractionated radiotherapy and concomitant chemotherapy for recurrent or progressive glioblastoma
Evaluated in this study were the feasibility and the efficacy of concurrent low dose fractionated radiotherapy (LD-FRT) and chemotherapy as palliative treatment for recurrent/progressive glioblastoma multiform...
-
Article
AlN thin films prepared by ArF plasma assisted PLD. Role of process conditions on electronic and chemical–morphological properties
Aluminium nitride thin films were deposited on n-Si <100> substrates by RF plasma activated reactive pulsed laser deposition (PLD). An ArF excimer pulsed laser, 10 Hz and 2.5 J/cm2 energy fluence, has been used t...