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  1. Article

    Open Access

    A cost-effectiveness analysis of an integrated clinical-radiogenomic screening program for the identification of BRCA 1/2 carriers (e-PROBE study)

    Current approach to identify BRCA 1/2 carriers in the general population is ineffective as most of the carriers remain undiagnosed. Radiomics is an emerging tool for large scale quantitative analysis of featur...

    A. Di Pilla, C. Nero, M. L. Specchia, F. Ciccarone, L. Boldrini in Scientific Reports (2024)

  2. No Access

    Chapter

    Brachytherapy for Nose Vestibule Malignancies: Functional Results

    Nasal cavity is part of the respiratory system with multiple delicate functions, which can be compromised by different pathological conditions and also as a result of treatments. Surgical treatment of nose ves...

    Jacopo Galli, Francesco Bussu, Giulio Cesare Passali in Malignancies of the Nasal Vestibule (2023)

  3. No Access

    Article

    Stereotactic radiosurgery for bone metastases in oligometastatic prostate cancer patients: DESTROY-2 clinical trial subanalysis

    Aim of this analysis was to report toxicity and clinical outcomes in oligorecurrent prostate cancer (PCa) patients treated with single fraction stereotactic radiosurgery (SRS) for bone metastases.

    F. Deodato, D. Pezzulla, S. Cilla, M. Ferro in Clinical and Translational Oncology (2022)

  4. No Access

    Article

    Stereotactic body radiotherapy to lymph nodes in oligoprogressive castration-resistant prostate cancer patients: a post hoc analysis from two phase I clinical trials

    The prognosis of prostate cancer (PC) is generally favorable but the incidence of metastases is relatively high after the treatment of the primary tumor, especially in high-risk patients. Fractionated stereota...

    D. Pezzulla, G. Macchia, S. Cilla, M. Buwenge in Clinical & Experimental Metastasis (2021)

  5. No Access

    Article

    Preoperative chemoradiotherapy affects postoperative outcomes and functional results in patients treated with transanal endoscopic microsurgery for rectal neoplasms

    The aim of this study was to quantify the incidence of short-term postoperative complications and functional disorders at 1 year from transanal endoscopic microsurgery (TEM) for rectal neoplasms, to compare pa...

    G. Rizzo, D. P. Pafundi, F. Sionne, L. D’Agostino in Techniques in Coloproctology (2021)

  6. Article

    Open Access

    Recent advances in (chemo-)radiation therapy for rectal cancer: a comprehensive review

    The role of radiation therapy in the treatment of (colo)-rectal cancer has changed dramatically over the past decades. Introduced with the aim of reducing the high rates of local recurrences after conventional...

    F. Roeder, E. Meldolesi, S. Gerum, V. Valentini, C. Rödel in Radiation Oncology (2020)

  7. No Access

    Chapter

    Microvascular Techniques

    Reconstructive microsurgery has become an integral part of head and neck reconstructive surgery, allowing the completion of complex resections with predictable outcome. These improvements are related to techno...

    V. Valentini, M. Della Monaca in Free Flaps in Head and Neck Reconstruction (2020)

  8. Article

    Open Access

    MR-guidance in clinical reality: current treatment challenges and future perspectives

    Magnetic Resonance-guided radiotherapy (MRgRT) marks the beginning of a new era. MR is a versatile and suitable imaging modality for radiotherapy, as it enables direct visualization of the tumor and the surrou...

    S. Corradini, F. Alongi, N. Andratschke, C. Belka, L. Boldrini in Radiation Oncology (2019)

  9. No Access

    Article

    IMproved MAnagement (IM-MA study) in cancer-related pain: the value of a joint approach by an integrated team of radiotherapist and anesthetist

    Purpose of this study was to retrospectively review our experience of multidisciplinary clinic providing a joint approach by radiation oncologist and anesthetist for patients with cancer pain to evaluate the a...

    S. Manfrida, V. Masiello, F. Cellini, E. Adducci, L. Polidori in Supportive Care in Cancer (2019)

  10. No Access

    Article

    Multidisciplinary team in head and neck cancer: a management model

    Nowadays, the multidisciplinary team (MDT) is an essential component for oncologic disease management. Its benefit is also extensively recognized in head and neck cancer (HNC) community, due to tumor rarity an...

    F. De Felice, V. Tombolini, M. de Vincentiis, G. Magliulo, A. Greco in Medical Oncology (2018)

  11. No Access

    Article

    The PRICE study: The role of conventional and diffusion-weighted magnetic resonance imaging in assessment of locally advanced cervical cancer patients administered by chemoradiation followed by radical surgery

    To analyse the role of DW-MRI in early prediction of pathologically-assessed residual disease in locally-advanced cervical cancer (LACC) treated with neoadjuvant chemoradiotherapy followed by radical surgery.

    A. L. Valentini, M. Miccò, B. Gui, M. Giuliani, E. Rodolfino in European Radiology (2018)

  12. No Access

    Article

    Authors’ reply to “Rectal sparing approach after preoperative radio- and/or chemotherapy (RESARCH) in patients with rectal cancer: potential pitfalls of a multicentre observational study”

    S. Pucciarelli, V. Valentini, C. Aschele, A. Barina in Techniques in Coloproctology (2018)

  13. No Access

    Chapter

    What Is the Ongoing Recommendation in the Management of Rectal Cancer?

    During the past 20 years, we have seen major changes in the way patients with rectal cancer are investigated and treated. The key components are the improvements in preoperative staging, in surgical technique ...

    V. Valentini, Hans-Joachim Schmoll in Multidisciplinary Management of Rectal Can… (2018)

  14. No Access

    Article

    Role of Inflammatory Diseases in Hypertension

    Chronic inflammatory diseases (CID) are characterized by an increased risk of cardiovascular (CV) morbidity and mortality. Several mechanisms, including early acceleration of subclinical atherosclerotic damage...

    E. Bartoloni, A. Alunno, V. Valentini in High Blood Pressure & Cardiovascular Preve… (2017)

  15. No Access

    Article

    Rectal sparing approach after preoperative radio- and/or chemotherapy (RESARCH) in patients with rectal cancer: a multicentre observational study

    Rectum-sparing approaches appear to be appropriate in rectal cancer patients with a major (mCR) or complete clinical response (cCR) after neoadjuvant therapy. The aim of the present study is to evaluate the e...

    A. Barina, A. De Paoli, P. Delrio, M. Guerrieri in Techniques in Coloproctology (2017)

  16. No Access

    Article

    Infrared absorption of fs-laser textured CVD diamond

    Nanoscale periodic texturing on polycrystalline CVD diamond surface was performed to obtain a significant increase in optical absorptance to visible and near-infrared radiation. Surface texturing, obtained by...

    P. Calvani, A. Bellucci, M. Girolami, S. Orlando, V. Valentini in Applied Physics A (2016)

  17. Article

    Open Access

    Optical properties of femtosecond laser-treated diamond

    A laser-induced periodic surface structure (LIPSS) has been fabricated on polycrystalline diamond by an ultrashort Ti:Sapphire pulsed laser source (λ = 800 nm, P = 3 mJ, 100 fs) in a high vacuum chamber (<10−7 mb...

    P. Calvani, A. Bellucci, M. Girolami, S. Orlando, V. Valentini in Applied Physics A (2014)

  18. No Access

    Article

    Raman investigation of femtosecond laser-induced graphitic columns in single-crystal diamond

    We report on the fabrication of graphitic columns induced in single-crystal diamond plates using 100 fs laser pulses at 800 nm wavelength. Different values of laser fluence (0.6–1.2 J/cm2) and graphitization spee...

    M. Girolami, A. Bellucci, P. Calvani, S. Orlando, V. Valentini in Applied Physics A (2014)

  19. No Access

    Article

    Low-dose fractionated radiotherapy and concomitant chemotherapy for recurrent or progressive glioblastoma

    Evaluated in this study were the feasibility and the efficacy of concurrent low dose fractionated radiotherapy (LD-FRT) and chemotherapy as palliative treatment for recurrent/progressive glioblastoma multiform...

    M. Balducci, B. Diletto, S. Chiesa, G.R. D’Agostino in Strahlentherapie und Onkologie (2014)

  20. No Access

    Article

    AlN thin films prepared by ArF plasma assisted PLD. Role of process conditions on electronic and chemical–morphological properties

    Aluminium nitride thin films were deposited on n-Si <100> substrates by RF plasma activated reactive pulsed laser deposition (PLD). An ArF excimer pulsed laser, 10 Hz and 2.5 J/cm2 energy fluence, has been used t...

    E. Cappelli, D. M. Trucchi, S. Orlando, V. Valentini, A. Mezzi in Applied Physics A (2014)

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