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Chapter
Galectins and Other Endogenous Carbohydrate-Binding Proteins of Animal Bladder
Defects in the glycocalyx of the bladder epithelium may be related to the opment of bladder diseases including interstitial cystitis which is a chronic bladder e of unknown etiology. Indirect evidence has impl...
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Article
Purification and characterization of the MUC1 mucin-type glycoprotein, epitectin, from human urine: structures of the major oligosaccharide alditols
The MUC1 glycoprotein, epitectin, a component of the human bladder epithelium, was purified from human urine. Sedimentation equilibrium analysis and gel filtration using polysaccharide or protein standards rev...
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Article
Modification and introduction of various radioactive labels into the sialic acid moiety of sialoglycoconjugates
A method for modifying and isotopic labeling the sialyl moiety of sialoglycoproteins is described. The basis of the procedure is the reductive amination of the exocyclic aldehyde group, generated on sialic aci...
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Article
Modification of sialyl residues of gonadotropic hormones by reductive amination. Influence on biological activity and circulating half-life
The sialic acid residues of human chorionic gonadotropin, human lutropin and human follitropin were quantitatively modified by introduction of an amino compound. In radioreceptor assays, the modified chorionic...
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Article
Isolation and characterization of membrane-associated proteoglycans from normal and malignant human mammary epithelial cells
The plasma membrane-associated proteoglycans of a malignant human breast cell line (MDA-MB-231) were compared with the corresponding proteoglycans from a normal cell line (HBL-100). The labeled proteoglycans w...
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Article
Structure and function of the Ca antigen
The Ca antigen, which can be detected in a wide range of malignant human tumours by means of the Cal antibody, is a glycoprotein of the mucin type. At least 95% of the carbohydrate is 0-glycosidically linked t...
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Chapter
Abstracts of Free Communications
The surface mucous cells of gastric fundus secrete mucous glycoprotein which covers the inner surface of the stomach. Subcellular fractionation of gastric scra**s in sucrose density gradients yielded a micro...
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Article
Interaction between the soluble and particulate neuraminidases of chick liver
The sum of the neuraminidase activities found in the isolated soluble and particulate fractions of chick liver was considerably higher than that observed in the cytoplasmic extract from which these fractions w...
