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Article
−295 T-to-C promoter region IL-16 gene polymorphism is associated with Whipple’s disease
Whipple’s disease (WD) is a rare systemic condition caused, in genetically predisposed subjects, by Tropheryma whipplei, a common bacterium widespread in the environment. The relevance of genetic predisposition i...
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Article
Cytokine genetic profile in Whipple’s disease
Whipple’s disease (WD) is a very rare chronic systemic condition characterised by a Th2/T regulatory (Treg) dysregulated immune response versus Tropheryma whipplei, a bacterium widely diffuse in the environment. ...
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Article
Changing paradigms in Whipple’s disease and infection with Tropheryma whipplei
More than a century after its first description through G.H. Whipple, the understanding of the chronic multisystemic infection called Whipple’s disease is still limited. However, within recent years the knowle...
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Article
Immunrekonstitutionssyndrom des Dünndarms bei einer immunsupprimierten Patientin mit systemischem Lupus erythematodes und nichttuberkulöser Mykobakteriose
Eine überschießende Immunreaktion mit granulomatöser Entzündung nach Infektionen mit opportunistischen Pathogenen wird als inflammatorisches Immunrekonstitutionssyndrom (IRIS) bezeichnet. Es wird in der Litera...
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Article
Regulation of Expression of Cytokines and Growth Factors in Osteoarthritic Cartilage Explants
Osteoarthritis (OA) is a degenerative joint disease characterised by the breakdown of the extracellular matrix of chondrocytes in the affected joints. Cytokines and growth factors which are known to play a ro...