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  1. No Access

    Article

    Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199)

    Duvelisib, an oral dual inhibitor of PI3K-δ and PI3K-γ, is in phase III trials for the treatment of chronic lymphocytic leukemia (CLL) and indolent non-Hodgkin’s lymphoma. In CLL, duvelisib monotherapy is asso...

    V M Patel, K Balakrishnan, M Douglas, T Tibbitts, E Y Xu, J L Kutok, M Ayers… in Leukemia (2017)

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    Chapter

    Are Heart Attacks Really Brain Attacks?

    In 1664, Thomas Willis recognized that the brain and the cardiovascular system are interdependent-when he wrote De Anatome Cerebri (Willis 1664). For the relief of angina pain, Francois Franck, in 1899, proposed ...

    S. R. Levine, V. M. Patel, K. M. A. Welch, J. E. Skinner in The Heart and Stroke (1987)