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Chromosome differentiation using nucleases: an overview
The era of the longitudinal differentiation of metaphase chromosomes (chromosome banding) dawned in 1968 when Caspersson and coworkers described the use of quinacrine mustard as a fluorescent compound which he...
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Article
Electron microscopy and biochemical analysis of mouse metaphase chromosomes after digestion with restriction endonucleases
Electron microscopy (EM) of whole mounted mouse chromosomes, light microscopy (LM), and agarose gel electrophoresis of DNA were used to investigate the cytological effect on chromosomes of digestion with the r...