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    Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts

    Historically, our understanding of mechanisms underlying human leukemogenesis are inferred from genetically engineered mouse models. Relatively, few models that use primary human cells recapitulate the full le...

    A P A Theocharides, S M Dobson, E Laurenti, F Notta, V Voisin, P-Y Cheng… in Leukemia (2015)