8 Result(s)
within
V Cuomo
Neurosciences
Psychiatry
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Article
Open AccessThe NADPH oxidase NOX2 as a novel biomarker for suicidality: evidence from human post mortem brain samples
Recent evidence points towards a role of oxidative stress in suicidality. However, few studies were carried out on the sources of reactive oxygen species (ROS) in subjects with suicidal behaviour. We have prev...
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Article
Open AccessNADPH oxidase elevations in pyramidal neurons drive psychosocial stress-induced neuropathology
Oxidative stress is thought to be involved in the development of behavioral and histopathological alterations in animal models of psychosis. Here we investigate the causal contribution of reactive oxygen speci...
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Article
Short- and long-term consequences of prenatal exposure to the cannabinoid agonist WIN55,212-2 on rat glutamate transmission and cognitive functions
The aim of the present review is to summarize integrated neurochemical, morphological and neurobehavioral evidence, in particular from our laboratory, which emphasize the short- and long-term consequences of p...
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Article
Irreversible impairment of active avoidance behavior in rats prenatally exposed to mild concentrations of carbon monoxide
Wistar female rats were exposed to relatively mild concentrations of carbon monoxide (75 and 150 ppm) from day 0 to day 20 of pregnancy. The results show that prenatal exposure to CO (150 ppm) significantly im...
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Article
Behavioural responsiveness to muscimol and apomorphine 2 months after prolonged treatment with estradiol in rats
Two months after prolonged administration of estradiol (ES) in female rats the behavioural responsiveness to muscimol, a GABA receptor stimulating agent, and to apomorphine, a dopamine receptor agonist, was si...
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Article
Early postnatal chlordiazepoxide administration: Permanent behavioural effects in the mature rat and possible involvement of the GABA-benzodiazepine system
The long term behavioural and biochemical effects of chronic chlordiazepoxide treatment during the period of neuronal maturation in the rat have been investigated. The administration to lactating mothers of ch...
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Article
Behavioural and biochemical effects in the adult rat after prolonged postnatal administration of clozapine
Rats were administered 10 mg/kg SC of clozapine (C) or vehicle solution (S) daily from day 1 after birth until 20 days of age. At 60 days of age (40 days after the postnatal treatment with C or S was interrupt...
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Article
Enduring behavioural and biochemical effects in the adult rat after prolonged postnatal administration of haloperidol
Rats were administered 0.5 mg/kg SC of haloperidol (H) or saline (S) daily from day 1 after birth until 20 days of age. At 60 days of age (40 days after the postnatal treatment with H or S was interrupted) the...
