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Article
Irreversible impairment of active avoidance behavior in rats prenatally exposed to mild concentrations of carbon monoxide
Wistar female rats were exposed to relatively mild concentrations of carbon monoxide (75 and 150 ppm) from day 0 to day 20 of pregnancy. The results show that prenatal exposure to CO (150 ppm) significantly im...
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Chapter and Conference Paper
Developmental Neurotoxicity of Carbon Monoxide
The results of recent studies dealing with behavioral and electrophysiological dysfunctions induced in rat offspring by prenatal exposure to relatively mild CO concentrations (75 and 150 ppm) have been reviewe...
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Chapter and Conference Paper
Behavioural and Neurochemical Changes Produced by Lefetamine in Two Inbred Strains of Mice
Lefetamine, a diphenylalkylaminic derivative, is a centrally acting analgesic which seems to possess abuse liability. The analgesic effect and the abuse liability of this compound are both due to its opiate ac...
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Article
Valutazione dei dati aerosporologici ottenuti in due diverse stazioni di rilevamento di una stessa città
Nel presente lavoro vengono riportati gli studi quantitativi e qualitativi delle spore micetiche presenti in due diverse zone della città di Cagliari. I rilevamenti sono stati effettuati nei mesi di Febbraio, ...
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Chapter and Conference Paper
Prenatal Exposure to Methylazoxymethanol (MAM) Acetate: Effects on Ultrasonic Vocalization and Locomotor Activity in Rat Offspring
Methylazoxymethanol (MAM), a potent alkylating agent, produces marked microencephaly as well as long-term learning impairments in the progeny of rats injected at the beginning of the 3rd week of pregnancy (Spa...
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Article
Biochemical and behavioral changes in rats after prolonged treatment with desipramine: interaction with p-chlorophenylalanine
The decrease in the B max value of 3H-dihydroalprenolol (3H-DHA) binding to cortical membranes of rat brain induced by long-term administration of desipramine (DMI) was prevented by concomitant treatment with par...
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Article
Behavioural responsiveness to muscimol and apomorphine 2 months after prolonged treatment with estradiol in rats
Two months after prolonged administration of estradiol (ES) in female rats the behavioural responsiveness to muscimol, a GABA receptor stimulating agent, and to apomorphine, a dopamine receptor agonist, was si...
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Chapter and Conference Paper
Behavioural Changes in Rats After Prenatal Administration of Typical and Atypical Antidepressants
Prenatal administration of typical (desipramine, DMI) and atypical (viloxazine, VX and mianserin, MS) antidepressants, at dose levels which do not influence reproductive success or neonatal mortality, produces...
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Article
Early postnatal chlordiazepoxide administration: Permanent behavioural effects in the mature rat and possible involvement of the GABA-benzodiazepine system
The long term behavioural and biochemical effects of chronic chlordiazepoxide treatment during the period of neuronal maturation in the rat have been investigated. The administration to lactating mothers of ch...
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Article
Behavioural and biochemical effects in the adult rat after prolonged postnatal administration of clozapine
Rats were administered 10 mg/kg SC of clozapine (C) or vehicle solution (S) daily from day 1 after birth until 20 days of age. At 60 days of age (40 days after the postnatal treatment with C or S was interrupt...
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Article
Enduring behavioural and biochemical effects in the adult rat after prolonged postnatal administration of haloperidol
Rats were administered 0.5 mg/kg SC of haloperidol (H) or saline (S) daily from day 1 after birth until 20 days of age. At 60 days of age (40 days after the postnatal treatment with H or S was interrupted) the...