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Article
Irreversible impairment of active avoidance behavior in rats prenatally exposed to mild concentrations of carbon monoxide
Wistar female rats were exposed to relatively mild concentrations of carbon monoxide (75 and 150 ppm) from day 0 to day 20 of pregnancy. The results show that prenatal exposure to CO (150 ppm) significantly im...
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Article
Behavioural responsiveness to muscimol and apomorphine 2 months after prolonged treatment with estradiol in rats
Two months after prolonged administration of estradiol (ES) in female rats the behavioural responsiveness to muscimol, a GABA receptor stimulating agent, and to apomorphine, a dopamine receptor agonist, was si...
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Article
Early postnatal chlordiazepoxide administration: Permanent behavioural effects in the mature rat and possible involvement of the GABA-benzodiazepine system
The long term behavioural and biochemical effects of chronic chlordiazepoxide treatment during the period of neuronal maturation in the rat have been investigated. The administration to lactating mothers of ch...
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Article
Behavioural and biochemical effects in the adult rat after prolonged postnatal administration of clozapine
Rats were administered 10 mg/kg SC of clozapine (C) or vehicle solution (S) daily from day 1 after birth until 20 days of age. At 60 days of age (40 days after the postnatal treatment with C or S was interrupt...
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Article
Enduring behavioural and biochemical effects in the adult rat after prolonged postnatal administration of haloperidol
Rats were administered 0.5 mg/kg SC of haloperidol (H) or saline (S) daily from day 1 after birth until 20 days of age. At 60 days of age (40 days after the postnatal treatment with H or S was interrupted) the...