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Article
Effect of colchicine injection prior to the initiating phase of two-stage skin carcinogenesis in mice
Colchicine injected 5, 9 and 24 h respectively before initiation (using s.c. injection of urethane for initiating action and TPA skin applications for promoting action, in female ICR mice) led to a significant...
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Article
Leukaemogenic action of phorbol in intact and thymectomized mice of different strains
Phorbol, the unesterified parent alcohol of the skin promoter TPA, was administered i.p., twice weekly, throughout the lifetime of mice of 7 inbred strains: males and females of AKR/J, C3Heb and BALB/c, and fe...
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Article
Phorbol as a possible systemic promoting agent for skin carcinogenesis
In a repetition of a previous experiment, using this time a 20-fold higher dose of phorbol, administered i.p. as potential (systemic) promoter for skin carcinogenesis, 6/22 (27%) of the treated mice (after a s...