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Article
Open AccessValidation of the SACOV-19 score for identifying patients at risk of complicated or more severe COVID-19: a prospective study
Identification of patients at risk of complicated or more severe COVID-19 is of pivotal importance, since these patients might require monitoring, antiviral treatment, and hospitalization. In this study, we pr...
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Article
Open AccessHow to exclude pulmonary embolism in patients hospitalized with COVID-19: a comparison of predictive scores
Pulmonary embolism (PE) is an important complication of Coronavirus disease 2019 (COVID-19). COVID-19 is associated with respiratory impairment and a pro-coagulative state, rendering PE more likely and difficu...
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Article
Open AccessPrediction of COVID-19 deterioration in high-risk patients at diagnosis: an early warning score for advanced COVID-19 developed by machine learning
While more advanced COVID-19 necessitates medical interventions and hospitalization, patients with mild COVID-19 do not require this. Identifying patients at risk of progressing to advanced COVID-19 might guid...
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Article
Open AccessDownregulation of SFRP1 is a protumorigenic event in hepatoblastoma and correlates with beta-catenin mutations
Hepatoblastoma (HB) and pediatric hepatocellular carcinoma (HCC) are the most common malignant liver tumors in childhood. Both tumor types exhibit genetic and epigenetic alterations in the WNT/β-catenin signal...
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Metabolic Biomarkers of Pancreatic Cancer
Patients with pancreatic cancer (PDAC) are usually diagnosed in advanced often incurable disease stages. Sensitive and specific markers are critical to support diagnostic and therapeutic management. Early non-...