42 Result(s)

Article

Expression of FLIP_Long and FLIP_Short in bone marrow mononuclear and CD34+ cells in patients with myelodysplastic syndrome: correlation with apoptosis

Several apoptosis-inducing systems, including Fas/Fas ligand and TNF-related apoptosis-inducing ligand (TRAIL) and its receptors, are upregulated in myelodysplastic syndrome (MDS). FLIP (FLICE (FAS-associated ...

M Benesch, U Platzbecker, J Ward, H J Deeg, W Leisenring in Leukemia (2003)

Article

P-glycoprotein-mediated drug efflux is a resistance mechanism of chronic myelogenous leukemia cells to treatment with imatinib mesylate

Imatinib (Glivec^®, STI571) is an intracellular acting drug that demonstrates high activity against BCR-ABL-positive chronic myelogenous leukemia (CML) or acute lymphoblastic leukemia (ALL). However, many patients...

T Illmer, M Schaich, U Platzbecker, J Freiberg-Richter, U Oelschlägel… in Leukemia (2004)

Article

Reduced intensity conditioning allows for up-front allogeneic hematopoietic stem cell transplantation after cytoreductive induction therapy in newly-diagnosed high-risk acute myeloid leukemia

There is substantial need to improve the outcome of patients with high-risk acute myeloid leukemia (AML). The clinical trial reported here investigated a new approach of up-front allogeneic hematopoietic stem ...

U Platzbecker, C Thiede, M Füssel, G Geissler, T Illmer, B Mohr, M Hänel… in Leukemia (2006)

Article

Imatinib mesylate does not impair the immunogenicity of human myeloid blood dendritic cells

R Wehner, M Wendisch, K Schäkel, M Bornhäuser, U Platzbecker, B Mohr, A Temme… in Leukemia (2006)

Article

Infusion of bcr/abl peptide-reactive donor T cells to achieve molecular remission of chronic myeloid leukemia after CD34⁺ selected allogeneic hematopoietic cell transplantation

M Bornhauser, C Thiede, J Babatz, J Schetelig, T Illmer, A Kiani, U Platzbecker… in Leukemia (2006)

Article

Association with the single-nucleotide polymorphism (Glu785Lys) of the granulocyte colony-stimulating factor receptor with myelodysplastic syndromes and acute myeloid leukemia with multlineage dysplasia

U Platzbecker, U Germing, U Schäkel, T Illmer, S Soucek, M Schaich, G Ehninger… in Leukemia (2006)

Article

Lenalidomide as induction therapy before allogeneic stem cell transplantation in a patient with proliferative CMML-2 and del(5q) not involving the EGR1 locus

U Platzbecker, B Mohr, M von Bonin, M Binder, J Schetelig, G Ehninger… in Leukemia (2007)

Article

Induction of Toll-like receptor 2 and 4 expression on CD4⁺ and CD8⁺ T cells in G-CSF-mobilized unrelated peripheral blood stem cell grafts during leukapheresis: impact on patient outcome

U Platzbecker, J Stoehlmacher, C Pabst, E Goekkurt, U Oelschlägel… in Leukemia (2008)

Article

Successful treatment of molecular relapse in NPM1-positive AML using 5-azacytidine

M Wermke, C Thiede, A Kiani, G Ehninger, M Bornhäuser, U Platzbecker in Leukemia (2010)

Article

Haploidentical bone marrow transplantation with post-grafting cyclophosphamide: multicenter experience with an alternative salvage strategy

S Tuve, J Gayoso, C Scheid, J Radke, A Kiani, D Serrano, U Platzbecker… in Leukemia (2011)

Article

Long-term transfusion independence in del(5q) MDS patients who discontinue lenalidomide

A A N Giagounidis, A Kulasekararaj, U Germing, R Radkowski, S Haase, P Petersen… in Leukemia (2012)

Article

Survival, prognostic factors and rates of leukemic transformation in 381 untreated patients with MDS and del(5q): A multicenter study

Myelodysplastic syndromes (MDS) with del(5q) are considered to have a benign course of the disease. In order to address the issue of the propensity of those patients to progress to acute myeloid leukemia (AML)...

U Germing, M Lauseker, B Hildebrandt, A Symeonidis, J Cermak, P Fenaux… in Leukemia (2012)

Article

Azacitidine and donor lymphocyte infusions as first salvage therapy for relapse of AML or MDS after allogeneic stem cell transplantation

The combination of azacitidine and donor lymphocyte infusions (DLI) as first salvage therapy for relapse after allogeneic transplantation (allo-HSCT) was studied in 30 patients with acute myeloid leukemia (AML; n

T Schroeder, A Czibere, U Platzbecker, G Bug, L Uharek, T Luft, A Giagounidis… in Leukemia (2013)

Article

Salvage therapy with azacitidine increases regulatory T cells in peripheral blood of patients with AML or MDS and early relapse after allogeneic blood stem cell transplantation

T Schroeder, J Fröbel, R-P Cadeddu, A Czibere, A Dienst, U Platzbecker, G Bug… in Leukemia (2013)

Article

Combination of Azacitidine and Lenalidomide in Myelodysplastic Syndromes or acute Myeloid Leukemia—a wise Liaison?

Treatment options for older patients with advanced myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) are limited and the prognosis remains poor, thereby warranting development of novel therapies....

U Platzbecker, U Germing in Leukemia (2013)

Article

SETBP1 mutation analysis in 944 patients with MDS and AML

F Thol, K J Suchanek, C Koenecke, M Stadler, U Platzbecker, C Thiede… in Leukemia (2013)

Article

Early intervention with allogeneic hematopoietic cell transplantation during chemotherapy-induced aplasia in patients with high-risk acute myeloid leukemia

F Stölzel, U Platzbecker, B Mohr, C Röllig, J M Middeke, C Thiede, M Füssel… in Leukemia (2013)

Article

Impact of the revised International Prognostic Scoring System on the outcome of patients with acute myeloid leukemia with or without antecedent myelodysplastic syndrome

F Stölzel, M Kramer, B Mohr, M Wermke, M Bornhäuser, G Ehninger, M Schaich… in Leukemia (2014)