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Article
Long-term transfusion independence in del(5q) MDS patients who discontinue lenalidomide
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Article
Identification of disease- and therapy-associated proteome changes in the sera of patients with myelodysplastic syndromes and del(5q)
Using ProteinChip array technology, which is based on the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, we performed proteomic analyses on sera from myelodysplastic syndromes (...
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Article
Refinement of the international prognostic scoring system (IPSS) by including LDH as an additional prognostic variable to improve risk assessment in patients with primary myelodysplastic syndromes (MDS)
The international prognostic scoring system (IPSS) is considered the gold standard for risk assessment in primary myelodysplastic syndromes (MDS). This score includes several prognostic factors except serum la...
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Article
Prognosis of patients with del(5q) MDS and complex karyotype and the possible role of lenalidomide in this patient subgroup
The survival of patients with myelodysplastic syndromes is strongly affected by chromosomal abnormalities. Patients with an isolated del(5q31) have a favourable prognosis that worsens with the addition of anot...
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Article
Early plasmacytoid dendritic cell leukemia/lymphoma coexpressing myeloid antigenes
Early plasmacytoid dendritic cell (pDC) leukemia/lymphoma has recently been described as a CD4+CD56+ lineage negative malignancy with characteristic clinical, morphologic, immunophenotypic, and biological feature...
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Article
Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31
We analyzed data of 76 consecutive patients with myelodysplastic syndrome (MDS) and isolated del(5q) (n=66) or del(5q) plus one additional chromosomal abnormality (n=10) included in our MDS database over the last...
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Article
Fournier's gangrene
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Chapter and Conference Paper
Severe Laryngeal Edema in Acute Promyelocytic Leukemia under All-Trans Retinoic Acid
All-trans retinoic acid (ATRA) has become a valuable agent in the treatment of acute promyelocytic leukemia (APL). However, administration is complicated by the frequently observed“Retinoic Acid Syndrome”(RAS)...
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Chapter and Conference Paper
Acute Promyelocytic Leukemia and Pregnancy
Observations that vitamin- A- deficient rats develop premalignant epidermal lesions that are reversible with repletion of retinoids (Wolbach et al. 1925) first suggested that vitamin A derivatives might play a...
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Article
Pseudomonas aeruginosa blepharoconjunctivitis during cytoreductive chemotherapy in a woman with acute lymphocytic leukemia
Patients undergoing chemotherapy regimens for hematologic malignancies are prone to develop unusual and potentially life-threatening infections during periods of leukopenia- induced immunosuppression. We repo...
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Article
Pathologic rupture of the spleen in hematologic malignancies: two additional cases
Pathologic rupture of the spleen in hematologic malignancies is rare. We present two cases of splenic rupture which occurred in a man with a secondary high-grade non-Hodgkin's lymphoma and a woman with chroni...