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  1. No Access

    Article

    The role of Smad signaling in hematopoiesis and translational hematology

    Hematopoietic stem cells (HSCs) reside in the bone marrow (BM) of adult individuals and function to produce and regenerate the entire blood and immune system over the course of an individual's lifetime. Histor...

    U Blank, S Karlsson in Leukemia (2011)

  2. No Access

    Article

    Increased formation of VAMP-3-containing SNARE complexes in mast cells from VAMP-8 deficient cells

    N. Tiwari, C-C. Wang, C. Brochetta, L. Scandiuzzi, W. Hong… in Inflammation Research (2009)

  3. No Access

    Article

    H2O2 impairs inflammatory mediator release from immunologically stimulated RBL-2H3 cells through a redox-sensitive, calcium-dependent mechanism

    Objectives: In this study we examined the effects of the inflammatory agent hydrogen peroxide (H2O2) on IgE-mediated mast cell responses.¶Materials and methods: Release of preformed gran...

    C. Guérin-Marchand, H. Sénéchal, C. Pelletier, H. Fohrer… in Inflammation Research (2001)

  4. No Access

    Article

    Specific signaling pathways in the regulation of TNF-α mRNA synthesis and TNF-α secretion in RBL-2H3 mast cells stimulated through the high affinity IgE receptor

    Objective: In the present study, we investigated signal transduction pathways involved in TNF-α gene expression and TNF-α secretion by mast cells stimulated through the high affinity IgE...

    C. Pelletier, C. Guérin-Marchand, B. Iannascoli, F. Marchand… in Inflammation Research (1998)

  5. No Access

    Chapter and Conference Paper

    The High Affinity Receptor for Immunoglobulin E: New Developments

    Over the last few years considerable progress has been made in the field of the high affinity receptor for immunoglobulin E (FcεRI). The recent achievements were made possible by the rapid development of the tech...

    J.-P. Kinet, H. Metzger, G. Alber, U. Blank, K. Huppi… in Progress in Immunology (1989)

  6. No Access

    Article

    Complete structure and expression in transfected cells of high affinity IgE receptor

    The high-affinity receptor for immunoglobulin E, Fcɛ RI, is found exclusively on mast cells and basophils. When multivalent aller-gens bind to the receptor-bound IgE, the consequent aggregation of the receptors l...

    U. Blank, C. Ra, L. Miller, K. White, H. Metzger, J.-P. Kinet in Nature (1989)