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    Article

    Gene regulatory networks in disease and ageing

    The precise control of gene expression is required for the maintenance of cellular homeostasis and proper cellular function, and the declining control of gene expression with age is considered a major contribu...

    Paula Unger Avila, Tsimafei Padvitski, Ana Carolina Leote in Nature Reviews Nephrology (2024)

  2. Article

    Open Access

    Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling

    Organismal physiology and survival are influenced by environmental conditions and linked to protein quality control. Proteome integrity is achieved by maintaining an intricate balance between protein folding a...

    Alexandra Segref, Kavya L. Vakkayil, Tsimafei Padvitski in Nature Communications (2022)

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    Article

    Expression of cellulose synthase-like genes in two phenotypically distinct flax (Linum usitatissimum L.) subspecies

    Cellulose synthase-like (CSL) genes encode glycosyltransferases thought to be involved in the biosynthesis of cell wall non-cellulosic polysaccharides; however, the exact function is not established yet for many ...

    Dmitry Galinousky, Tsimafei Padvitski in Genetic Resources and Crop Evolution (2020)