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  1. Article

    Open Access

    Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder

    Major depressive disorder (MDD) is known to cause significant disability. Genome-wide DNA methylation (DNAm) profiles can be used to estimate biological aging and as epigenetic clocks. However, information on ...

    Ryota Shindo, Takaki Tanifuji, Satoshi Okazaki, Ikuo Otsuka, Toshiyuki Shirai in npj Aging (2023)

  2. No Access

    Article

    Development of a compact dose verification system using a fluorescent screen for carbon-ion therapy

    For quality assurance (QA) of therapeutic ion beams, a QA tool having high spatial resolution and quick verification is required. An imaging system with a fluorescent screen is suitable for the QA procedure. W...

    Yousuke Hara, Takuji Furukawa, Kota Mizushima in Journal of the Korean Physical Society (2016)

  3. Article

    Open Access

    Carbon-ion scanning lung treatment planning with respiratory-gated phase-controlled rescanning: simulation study using 4-dimensional CT data

    To moving lung tumors, we applied a respiratory-gated strategy to carbon-ion pencil beam scanning with multiple phase-controlled rescanning (PCR). In this simulation study, we quantitatively evaluated dose dis...

    Wataru Takahashi, Shinichiro Mori, Mio Nakajima, Naoyoshi Yamamoto in Radiation Oncology (2014)

  4. No Access

    Book

    Carbon-Ion Radiotherapy

    Principles, Practices, and Treatment Planning

    Hirohiko Tsujii, Tadashi Kamada, Toshiyuki Shirai (2014)

  5. No Access

    Chapter

    Workflow of Carbon-Ion Radiotherapy

    The carbon-ion radiotherapy system consists of oncology information system (OIS), radiotherapy treatment planning system (RTPS), and beam delivery system (BDS), which is similar to the standard radiotherapy sy...

    Toshiyuki Shirai, Yuka Takei in Carbon-Ion Radiotherapy (2014)

  6. No Access

    Article

    Development of digital reconstructed radiography software at new treatment facility for carbon-ion beam scanning of National Institute of Radiological Sciences

    To increase the accuracy of carbon ion beam scanning therapy, we have developed a graphical user interface-based digitally-reconstructed radiograph (DRR) software system for use in routine clinical practice at...

    Shinichiro Mori, Taku Inaniwa in Australasian Physical & Engineering Scienc… (2012)

  7. No Access

    Article

    Characterization of thin-foil preformed plasmas for high-intensity laser plasma interactions

    We observe the electron density distribution of preformed plasmas of a titanium foil target with the 400 nm probe beam as an interferometer. The preformed plasma at the front side of the target is generated by...

    Akito Sagisaka, Hiroyuki Daido in Acta Physica Hungarica Series B, Quantum E… (2006)