4 Result(s)
within
Torben Rogge
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessData-driven design of new chiral carboxylic acid for construction of indoles with C-central and C–N axial chirality via cobalt catalysis
Challenging enantio- and diastereoselective cobalt-catalyzed C–H alkylation has been realized by an innovative data-driven knowledge transfer strategy. Harnessing the statistics of a related transformation as ...
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Article
Open AccessLate-stage peptide C–H alkylation for bioorthogonal C–H activation featuring solid phase peptide synthesis
Methods for the late-stage diversification of structurally complex peptides hold enormous potential for advances in drug discovery, agrochemistry and pharmaceutical industries. While C–H arylations emerged for...
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Article
Open AccessNickel-catalyzed reductive thiolation and selenylation of unactivated alkyl bromides
Chalcogen-containing compounds have received considerable attention because of their manifold applications in agrochemicals, pharmaceuticals, and material science. While many classical methods have been develo...
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Article
Open AccessRuthenium(II)-catalysed remote C–H alkylations as a versatile platform to meta-decorated arenes
The full control of positional selectivity is of prime importance in C–H activation technology. Chelation assistance served as the stimulus for the development of a plethora of ortho-selective arene functionaliza...
