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  1. No Access

    Article

    Enhanced BDNF Signaling is Associated with an Antidepressant-like Behavioral Response and Changes in Brain Monoamines

    1. Neurotrophins and serotonin have both been implicated in the pathophysiology of depression and in the mechani...

    Eija Koponen, Tomi Rantamäki, Vootele Voikar… in Cellular and Molecular Neurobiology (2005)

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    Article

    trkB-Receptor Activation Contributes to the Kainate-Induced Increase in BDNF mRNA Synthesis

    1. The expression of brain-derived neurotrophic factor (BDNF) mRNA is induced by neuronal activity through increased intracellular calcium. As BDNF also increases intracellular calcium levels through trkB acti...

    Tommi Saarelainen, Sari Vaittinen, Eero Castrén in Cellular and Molecular Neurobiology (2001)

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    Article

    Expression of the naturally occurring truncated trkB neurotrophin receptor induces outgrowth of filopodia and processes in neuroblastoma cells

    We have investigated the effects of the truncated trkB receptor isoform T1 (trkB.T1) by transient transfection into mouse N2a neuroblastoma cells. We observed that expression of trkB.T1 leads to a striking cha...

    Annakaisa Haapasalo, Tommi Saarelainen, Maxim Moshnyakov, Urmas Arumäe… in Oncogene (1999)