-
Article
Open AccessSagace: A web-based search engine for biomedical databases in Japan
In the big data era, biomedical research continues to generate a large amount of data, and the generated information is often stored in a database and made publicly available. Although combining data from mult...
-
Article
Open AccessWhole-genome sequencing and analysis of the Malaysian cynomolgus macaque (Macaca fascicularis) genome
The genetic background of the cynomolgus macaque (Macaca fascicularis) is made complex by the high genetic diversity, population structure, and gene introgression from the closely related rhesus macaque (Macaca m...
-
Article
Use of BAC array CGH for evaluation of chromosomal stability of clinically used human mesenchymal stem cells and of cancer cell lines
Array-based comparative genomic hybridization (aCGH) using bacterial artificial chromosomes (BAC) is a powerful method to analyze DNA copy number aberrations of the entire human genome. In fact, CGH and aCGH h...
-
Article
Proceedings of The 28th Annual Meeting of the Japan Human Cell Society 23 August 2009 Tsukuba, Ibaraki, Japan
-
Protocol
An Outgrowth Culture System of Normal Human Epithelium
In order to study the growth regulation of normal human epithelium, we have developed an outgrowth culture system (1). Cinematographic observation has revealed that the cells migrate and proliferate in a coordina...
-
Article
Immunolocalization of hepatocyte growth factor and its receptor (c-Met) during mouse liver development
Although hepatocyte growth factor (HGF) was discovered as a potent hepatotrophic factor responsible for liver regeneration and may involve some organ development in embryogenesis, it remains to be revealed wh...
-
Article
Establishment of an outgrowth culture system to study growth regulation of normal human epithelium
To study the growth regulation of epithelial cells as a sheet, I developed an outgrowth culture system for normal human ectocervical epithelial (NHCE) cells, whereby outgrowths from tissue explants increase th...
-
Chapter
Cellular and Molecular Studies of Growth, Differentiation and Neoplastic Transformation of Human Bronchial Epithelial Cells in Vitro
Normal human cells in vitro appear to retain many normal phenotypic properties, remain diploid, eventually undergo senescence and rarely, if ever “spontaneously” transform to malignant cells. Retained properties ...
