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Open AccessBiological and mechanical performance of calcium phosphate cements modified with phytic acid
Calcium phosphate cements, primarily brushite cements, require the addition of setting retarders to ensure adequate processing time and processability. So far, citric acid has been the primary setting retarder...
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Article
Open AccessBesonderheiten und Probleme der Psychopharmakologie im Kindes- und Jugendalter
Die medikamentöse Behandlung von psychischen Erkrankungen im Kindes- und Jugendalter stellt eine besondere klinische und rechtliche Herausforderung dar. Gründe hierfür sind u. a. die häufig notwendigen Off-Lab...
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Open AccessIdentifying Symptoms of ADHD and Disruptive Behavior Disorders Most Strongly Associated with Functional Impairment in Children: A Symptom-Level Approach
To enhance the understanding of how symptoms of attention-deficit/hyperactivity disorder (ADHD) and disruptive behavior disorders such as oppositional defiant disorder (ODD), conduct disorder (CD), including c...
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Open AccessNovel adhesive mineral-organic bone cements based on phosphoserine and magnesium phosphates or oxides
Present surgical situations require a bone adhesive which has not yet been developed for use in clinical applications. Recently, phosphoserine modified cements (PMC) based on mixtures of o-phosphoserine (OPLS)...
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Open AccessThe effect of hemoadsorption on rivaroxaban blood plasma concentration in emergency cardiac surgery
Hemoadsorption was used in a 59-year-old patient with an acute type A aortic dissection, who was on rivaroxaban and dual antiplatelet therapy with clopidogrel and acetylsalicylic acid. Our aim was to expeditio...
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Open AccessAssessment framework of actor strategies in international river basin management, the case of Deltarhine
The combined effects of socio-economic growth as well as climate change exert increasing pressure on international river basins and require dedicated cooperative efforts to jointly manage international rivers....
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Open AccessIndividualised stepwise adaptive treatment for 3–6-year-old preschool children impaired by attention-deficit/hyperactivity disorder (ESCApreschool): study protocol of an adaptive intervention study including two randomised controlled trials within the consortium ESCAlife
Attention-deficit/hyperactivity disorder (ADHD) is a psychosocially impairing and cost-intensive mental disorder, with first symptoms occurring in early childhood. It can usually be diagnosed reliably at presc...
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Targeting parental motivation for change in childhood obesity: development and validation of the PURICA-S scale
The high prevalence of overweight and obesity in childhood and adolescence call for effective and sustainable intervention strategies. Parental motivation for change may be a key factor in sustained behavioral...
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Open AccessPolicy entrepreneurs in international river basins—getting climate adaptation on the cross-border water policy agenda
In this study, we look at the role which water policy entrepreneurs play in promoting and stimulating climate adaptation measures in international river basins. In a Dutch-German case study in the Rhine delta,...
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Open AccessIndividualised short-term therapy for adolescents impaired by attention-deficit/hyperactivity disorder despite previous routine care treatment (ESCAadol)—Study protocol of a randomised controlled trial within the consortium ESCAlife
Despite the high persistence rate of attention-deficit/hyperactivity disorder (ADHD) throughout the lifespan, there is a considerable gap in knowledge regarding effective treatment strategies for adolescents w...
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Open AccessESCAschool study: trial protocol of an adaptive treatment approach for school-age children with ADHD including two randomised trials
The ESCAschool study addresses the treatment of school-age children with attention-deficit/hyperactivity disorder (ADHD) in a large multicentre trial. It aims to investigate three interrelated topics: (i) Clin...
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Verhaltens- und emotionale Störungen mit Beginn in der Kindheit und Jugend
Die Verhaltens- und emotionalen Störungen mit Beginn in der Kindheit und Jugend umfassen ein weites Spektrum verschiedener Störungen: Störungen der motorischen Aktivität und Aufmerksamkeit, Störungen des Sozia...
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Living Reference Work Entry In depth
Verhaltens- und emotionale Störungen mit Beginn in der Kindheit und Jugend
Die Verhaltens- und emotionalen Störungen mit Beginn in der Kindheit und Jugend umfassen ein weites Spektrum verschiedener Störungen: Störungen der motorischen Aktivität und Aufmerksamkeit, Störungen des Sozia...
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Article
PPP2R2C as a candidate gene of a temperament and character trait-based endophenotype of ADHD
There are several lines of evidence that the 4p16 region is a candidate locus of both attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder. None of the harbored candidate genes of this region w...
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Article
Pilot study: potential transcription markers for adult attention-deficit hyperactivity disorder in whole blood
Attention-deficit hyperactivity disorder (ADHD) is a common behavioural disorder that affects not only children and adolescents but also adults; however, diagnosis of adult ADHD is difficult because patients s...
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Article
Pilot study on HTR2A promoter polymorphism, −1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive–compulsive disorder
A previous study showed that a single nucleotide polymorphism (SNP), −1438G/A (rs6311), found in the transcriptional control region of the gene that encodes the serotonin-receptor 2A (HTR2A) was associated wit...
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Developmental comorbidity in attention-deficit/hyperactivity disorder
With the present review, we intend to highlight the importance of considering the age- and development-dependent occurrence of comorbidity in ADHD and to outline distinct trajectories of symptom progression wi...
