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  1. Article

    Open Access

    Modulation of anti-cardiac fibrosis immune responses by changing M2 macrophages into M1 macrophages

    Macrophages play a crucial role in the development of cardiac fibrosis (CF). Although our previous studies have shown that glycogen metabolism plays an important role in macrophage inflammatory phenotype, the ...

    Shiqi Chen, Kan Wang, Zhengfeng Fan, Tingwen Zhou, Rui Li… in Molecular Medicine (2024)

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  2. Article

    Open Access

    A gadoxetic acid-enhanced MRI-based model using LI-RADS v2018 features for preoperatively predicting Ki-67 expression in hepatocellular carcinoma

    To construct a gadoxetic acid-enhanced MRI (EOB-MRI) -based multivariable model to predict Ki-67 expression levels in hepatocellular carcinoma (HCC) using LI-RADS v2018 imaging features.

    Yingying Liang, Fan Xu, Qiuju Mou, Zihua Wang, Chuyin **ao… in BMC Medical Imaging (2024)

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  3. No Access

    Article

    CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer’s disease

    Alzheimer’s disease (AD) is the most common form of neurodegenerative disease featured with memory loss and cognitive function impairments. Chronic mitochondrial stress is a vital pathogenic factor for AD and ...

    Wenting **e, Dong Guo, Jieyin Li, Lei Yue, Qi Kang… in Cell Death & Differentiation (2022)

  4. No Access

    Article

    RNA-sequencing of human aortic valves identifies that miR-629-3p and TAGLN miRNA-mRNA pair involving in calcified aortic valve disease

    This study aimed to uncover the microRNA and messenger RNA (miRNA/mRNA) interactions in the pathophysiological process of calcified aortic valve disease (CAVD) of the human aortic valve. RNA sequencing of six ...

    Chunli Wang, Juanjuan Han, Ming Liu, Yuming Huang… in Journal of Physiology and Biochemistry (2022)