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Article
Open AccessEpigenetic age acceleration and risk of aortic valve stenosis: a bidirectional Mendelian randomization study
Aortic valve stenosis (AVS) is the most prevalent cardiac valve lesion in developed countries, and pathogenesis is closely related to aging. DNA methylation-based epigenetic clock is now recognized as highly a...
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Article
Open AccessGlutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis
The glutathione (GSH) system is considered to be one of the most powerful endogenous antioxidant systems in the cardiovascular system due to its key contribution to detoxifying xenobiotics and scavenging overr...
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Article
Open AccessEpigenetic modification associated with climate regulates betulin biosynthesis in birch
The Betula genus contains pentacyclic triterpenoid betulin known for its environmental adaptation and medicinal properties. However, the mechanisms underlying betulin biosynthesis responding to climate change rem...
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Article
Open AccessComparison of ticagrelor and clopidogrel on platelet function and prognosis in unstable angina
This study aims to compare the effects of ticagrelor and clopidogrel on platelet function, cardiovascular prognosis, and bleeding in patients with unstable angina pectoris.
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Article
Open AccessFunctional analysis of PagNAC045 transcription factor that improves salt and ABA tolerance in transgenic tobacco
Salt stress causes inhibition of plant growth and development, and always leads to an increasing threat to plant agriculture. Transcription factors regulate the expression of various genes for stress response ...
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Article
Open AccessGenome-wide identification and expression analysis of the xyloglucan endotransglucosylase/hydrolase gene family in poplar
Xyloglucan endotransglucosylase/hydrolase (XTH) family plays an important role in cell wall reconstruction and stress resistance in plants. However, the detailed characteristics of XTH family genes and their e...
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Article
Open AccessGenome-wide analysis and expression profile of the bZIP gene family in poplar
The bZIP gene family, which is widely present in plants, participates in varied biological processes including growth and development and stress responses. How do the genes regulate such biological processes? ...
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Article
Open AccessGenome-wide search and structural and functional analyses for late embryogenesis-abundant (LEA) gene family in poplar
The Late Embryogenesis-Abundant (LEA) gene families, which play significant roles in regulation of tolerance to abiotic stresses, widely exist in higher plants. Poplar is a tree species that has important ecol...
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Article
Ectopic expression of a poplar gene NAC13 confers enhanced tolerance to salinity stress in transgenic Nicotiana tabacum
NACs are one of the major transcription factor families in plants which play an important role in plant growth and development, as well as in adverse stress responses. In this study, we cloned a salt-inducible...
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Article
Open AccessTranscriptome analysis of salt-responsive and wood-associated NACs in Populus simonii × Populus nigra
NAC (NAM, ATAF1–2, and CUC2) family is one of the largest plant-specific transcription factor families known to play significant roles in plant development processes and stress responses.
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Article
Open AccessOver-expression of poplar NAC15 gene enhances wood formation in transgenic tobacco
NAC (NAM/ATAF/CUC) is one of the largest plant-specific transcription factor (TF) families known to play significant roles in wood formation. Acting as master gene regulators, a few NAC genes can activate seco...
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Article
Open AccessThe association of metabolic syndrome components and chronic kidney disease in patients with hypertension
Hypertension is a highly prevalent disease and the leading cause of chronic kidney disease (CKD). Metabolic syndrome could also be the risk factor for CKD. We sought to study the association between metabolic ...
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Article
Open AccessSodium Selenate Ameliorates Cardiac Injury Developed from High-Fat Diet in Mice through Regulation of Autophagy Activity
Obesity is often accompanied by dyslipidemia, high blood glucose, hypertension, atherosclerosis, and myocardial dysfunction. Selenate is a vital antioxidant in the cardiovascular system. The beneficial effects...
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Article
Over expression of TaFer gene from Tamarix androssowii improves iron and drought tolerance in transgenic Populus tomentosa
Ferritin, a universal intracellular protein, can store large amounts of iron and improve plant resistance to abiotic and biotic stress. In this study, a ferritin gene (TaFer) from Tamarix androssowii Litv. was tr...
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Article
Early evaluation of growth traits of Larix kaempferi clones
Early selection is an important method to shorten the breeding cycle for tree species, which may differ in the time for early selection. To evaluate the early selected time for Larix kaempferi, tree height and di...
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Article
PsnERF75 Transcription Factor from Populus simonii × P. nigra Confers Salt Tolerance in Transgenic Arabidopsis
ERF transcription factor involves in many aspects of plant development and response to both biotic and abiotic environmental stimuli. In this study, we provided evidence that PsnERF75 can improve the salt toleran...
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Article
Characterization of ERF76 promoter cloned from Populus simonii × P. nigra
The poplar transcription factor ERF76 gene is salt-inducible and plays an important role in regulating stress-related genes. To understand the regulatory mechanisms of ERF76 gene, the 1537-bp upstream DNA sequenc...
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Article
The Tamarix ferritin gene confers low-iron tolerance in transgenic tobacco
Ferritin is one of the important proteins that respond to various stresses in Tamarix androssowii. We cloned a full-length cDNA sequence of a ferritin gene from T. androssowii, named “TaF...
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Article
Structure analysis and expression pattern of the ERF transcription factor family in poplar
The ethylene response factor (ERF) family is one of the largest families of plant-specific transcription factors, and plays significant roles in plant growth and development, and stress tolerance processes. To...
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Article
Expression patterns of WRKY genes in di-haploid Populus simonii × P. nigra in response to osmotic stress and ABA treatment
In this study, 108 WRKY genes with complete conserved WRKY domain and zinc-finger motif were identified from poplar in silico, and they were classified into three subfamilies named I, II, and III. The WRKY member...
