-
Article
Open AccessYour move: A precision medicine framework for physical activity in aging
The accelerating digital health landscape, coupled with the proliferation of wearable devices and advanced neuroimaging, offers an unprecedented avenue to develop precision interventions for enhancing physical...
-
Article
Open AccessResting-state MRI functional connectivity as a neural correlate of multidomain lifestyle adherence in older adults at risk for Alzheimer’s disease
Prior research has demonstrated the importance of a healthy lifestyle to protect brain health and diminish dementia risk in later life. While a multidomain lifestyle provides an ecological perspective to volun...
-
Article
Open AccessResting state functional connectivity provides mechanistic predictions of future changes in sedentary behavior
Sedentary behaviors are increasing at the cost of millions of dollars spent in health care and productivity losses due to physical inactivity-related deaths worldwide. Understanding the mechanistic predictors ...
-
Article
Relationships Between Enriching Early-Life Experiences and Cognitive Function Later in Life Are Mediated by Educational Attainment
The study of how engagement in enriching cognitive, physical, and social activities in childhood impacts cognitive function decades later will advance our understanding of how modifiable lifestyle activities p...
-
Article
Exercise for Brain Health: An Investigation into the Underlying Mechanisms Guided by Dose
There is a strong link between the practice of regular physical exercise and maintenance of cognitive brain health. Animal and human studies have shown that exercise exerts positive effects on cognition throug...
-
Article
Open AccessReappraising the concept of massive transfusion in trauma
The massive-transfusion concept was introduced to recognize the dilutional complications resulting from large volumes of packed red blood cells (PRBCs). Definitions of massive transfusion vary and lack support...