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  1. Article

    Open Access

    Predicting and exploring network components involved in pathogenesis in the malaria parasite via novel subnetwork alignments

    Malaria is a major health threat, affecting over 40% of the world's population. The latest report released by the World Health Organization estimated about 207 million cases of malaria infection, and about 627...

    Hong Cai, Timothy G Lilburn, Chang** Hong, Jianying Gu, Rui Kuang in BMC Systems Biology (2015)

  2. Article

    Open Access

    Genomic Encyclopedia of Bacterial and Archaeal Type Strains, Phase III: the genomes of soil and plant-associated and newly described type strains

    The Genomic Encyclopedia of Bacteria and Archaea (GEBA) project was launched by the JGI in 2007 as a pilot project to sequence about 250 bacterial and archaeal genomes of elevated phylogenetic diversity. Herein, ...

    William B Whitman, Tanja Woyke, Hans-Peter Klenk in Standards in Genomic Sciences (2015)

  3. Article

    Open Access

    Genomic Encyclopedia of Type Strains, Phase I: The one thousand microbial genomes (KMG-I) project

    The Genomic Encyclopedia of Bacteria and Archaea (GEBA) project was launched by the JGI in 2007 as a pilot project with the objective of sequencing 250 bacterial and archaeal genomes. The two major goals of th...

    Nikos C. Kyrpides, Tanja Woyke, Jonathan A. Eisen in Standards in Genomic Sciences (2014)

  4. Article

    Open Access

    A novel subnetwork alignment approach predicts new components of the cell cycle regulatory apparatus in Plasmodium falciparum

    According to the World Health organization, half the world's population is at risk of contracting malaria. They estimated that in 2010 there were 219 million cases of malaria, resulting in 660,000 deaths and a...

    Hong Cai, Chang** Hong, Timothy G Lilburn, Armando L Rodriguez in BMC Bioinformatics (2013)

  5. Article

    Open Access

    Module-based subnetwork alignments reveal novel transcriptional regulators in malaria parasite Plasmodium falciparum

    Malaria causes over one million deaths annually, posing an enormous health and economic burden in endemic regions. The completion of genome sequencing of the causative agents, a group of parasites in the genus Pl...

    Hong Cai, Chang** Hong, Jianying Gu, Timothy G Lilburn, Rui Kuang in BMC Systems Biology (2012)

  6. Article

    Open Access

    Protease-associated cellular networks in malaria parasite Plasmodium falciparum

    Malaria continues to be one of the most severe global infectious diseases, responsible for 1-2 million deaths yearly. The rapid evolution and spread of drug resistance in parasites has led to an urgent need fo...

    Timothy G Lilburn, Hong Cai, Zhan Zhou, Yufeng Wang in BMC Genomics (2011)

  7. Article

    Open Access

    Comparative genomics of the family Vibrionaceae reveals the wide distribution of genes encoding virulence-associated proteins

    Species of the family Vibrionaceae are ubiquitous in marine environments. Several of these species are important pathogens of humans and marine species. Evidence indicates that genetic exchange plays an important...

    Timothy G Lilburn, Jianying Gu, Hong Cai, Yufeng Wang in BMC Genomics (2010)

  8. Article

    Open Access

    Genomic and systems evolution in Vibrionaceae species

    The steadily increasing number of prokaryotic genomes has accelerated the study of genome evolution; in particular, the availability of sets of genomes from closely related bacteria has facilitated the explora...

    Jianying Gu, Jennifer Neary, Hong Cai, Audrey Moshfeghian in BMC Genomics (2009)