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Open AccessPredicting and exploring network components involved in pathogenesis in the malaria parasite via novel subnetwork alignments
Malaria is a major health threat, affecting over 40% of the world's population. The latest report released by the World Health Organization estimated about 207 million cases of malaria infection, and about 627...
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Article
Open AccessGenomic Encyclopedia of Bacterial and Archaeal Type Strains, Phase III: the genomes of soil and plant-associated and newly described type strains
The Genomic Encyclopedia of Bacteria and Archaea (GEBA) project was launched by the JGI in 2007 as a pilot project to sequence about 250 bacterial and archaeal genomes of elevated phylogenetic diversity. Herein, ...
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Article
Open AccessGenomic Encyclopedia of Type Strains, Phase I: The one thousand microbial genomes (KMG-I) project
The Genomic Encyclopedia of Bacteria and Archaea (GEBA) project was launched by the JGI in 2007 as a pilot project with the objective of sequencing 250 bacterial and archaeal genomes. The two major goals of th...
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Article
Open AccessA novel subnetwork alignment approach predicts new components of the cell cycle regulatory apparatus in Plasmodium falciparum
According to the World Health organization, half the world's population is at risk of contracting malaria. They estimated that in 2010 there were 219 million cases of malaria, resulting in 660,000 deaths and a...
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Article
Open AccessModule-based subnetwork alignments reveal novel transcriptional regulators in malaria parasite Plasmodium falciparum
Malaria causes over one million deaths annually, posing an enormous health and economic burden in endemic regions. The completion of genome sequencing of the causative agents, a group of parasites in the genus Pl...
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Article
Open AccessProtease-associated cellular networks in malaria parasite Plasmodium falciparum
Malaria continues to be one of the most severe global infectious diseases, responsible for 1-2 million deaths yearly. The rapid evolution and spread of drug resistance in parasites has led to an urgent need fo...
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Article
Open AccessComparative genomics of the family Vibrionaceae reveals the wide distribution of genes encoding virulence-associated proteins
Species of the family Vibrionaceae are ubiquitous in marine environments. Several of these species are important pathogens of humans and marine species. Evidence indicates that genetic exchange plays an important...
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Article
Open AccessGenomic and systems evolution in Vibrionaceae species
The steadily increasing number of prokaryotic genomes has accelerated the study of genome evolution; in particular, the availability of sets of genomes from closely related bacteria has facilitated the explora...