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  1. Article

    Open Access

    Microfibrillar-associated protein 5 suppresses adipogenesis by inhibiting essential coactivator of PPARγ

    Femoral head necrosis is responsible for severe pain and its incidence is increasing. Abnormal adipogenic differentiation and fat cell hypertrophy of bone marrow mesenchymal stem cells increase intramedullary ...

    Tianlong Zhang, Haoran Li, Shiwei Sun, Wuling Zhou, Tieqi Zhang… in Scientific Reports (2023)

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  2. Article

    Open Access

    Microfibrillar-associated protein 5 regulates osteogenic differentiation by modulating the Wnt/β-catenin and AMPK signaling pathways

    Dysfunctional osteogenesis of bone marrow mesenchymal stem cells (BMSCs) plays an important role in osteoporosis occurrence and development. However, the molecular mechanisms of osteogenic differentiation rema...

    Haoran Li, Wuling Zhou, Shiwei Sun, Tianlong Zhang, Tieqi Zhang… in Molecular Medicine (2021)

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  3. No Access

    Article

    ATP-binding cassette g1 regulates osteogenesis via Wnt/β-catenin and AMPK signaling pathways

    The dysfunction of bone marrow mesenchymal stem cells (BMSCs) in balancing osteogenesis and adipogenesis plays an important role in the occurrence and development of osteoporosis. It’s still unknown that wheth...

    Lei Zhou, Shiwei Sun, Tieqi Zhang, Yueming Yu, Liang Xu… in Molecular Biology Reports (2020)