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Article
Pharmacokinetics and safety of a new generic lurasidone: a phase I bioequivalence study in healthy Chinese subjects
Latuda® is a novel antipsychotic drug for schizophrenia and bipolar depression. A bioequivalence trial was performed to investigate the bioequivalence of Latuda® and its generic drug lurasidone. Two independent t...
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Article
Open AccessAnalysis of influencing factors on long COVID in COVID-19 patients infected with omicron variant three months after discharge: a cross-sectional study
The purpose of this study is to analyze the influencing factors associated with Long-COVID in patients infected with Omicron variant of COVID-19 in Changchun City, Jilin Province, China three months after disc...
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Article
Pharmacokinetics and bioequivalence of two pomalidomide capsules in healthy chinese subjects under fasting and fed conditions
Imnovid® is an immunomodulatory drug with antineoplastic activity. The aim of this study was to evaluate the bioequivalence and safety of the generic drug pomalidomide (Chia Tai Tianqing Pharmaceutical Group C...
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Article
Open AccessPretreatment to terahertz absorption curves by narrow undulation constraint and Its quick implementation suggested by convex hull
In this work, a method of pretreating THz absorption curve is proposed, which leads to minimal range in absorption, reserving necessary undulation of curve for identification by convolutional neural network. T...
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Article
A rapid method for distinguishing similar gelatins based on terahertz spectrum
Distinguishing similar gelatins are essential for pharmaceutical administration and therapy based on traditional Chinese medicine. Differed from the conventional studies, this study focuses on a reaction-free ...
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Article
Ultrasensitive Optical Refractive Index Detection of NaCl and Alcohol Solutions Based on Weak Value Amplification
An ultrasensitive surface plasmon resonance (SPR) refractive index detection scheme based on weak value amplification is presented. Extremely low refractive index change (9.8 × 10−7 RIU) of sodium chloride soluti...
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Article
W-band Aperture-Type Scanning Near-Field Microscopy Using Tapered Plastic Probe
An aluminum-coated PMMA tapered probe with 50 μm aperture was employed in near-field imaging at 110 GHz. The probe was chosen for near-field imaging experiments according to finite-difference time-domain elect...
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Article
A Comparative Study of Non-destructive Evaluation of Glass Fiber Reinforced Polymer Composites Using Terahertz, X-ray, and Ultrasound Imaging
A set of samples of glass fiber reinforced polymer composites with Teflon inclusions in the shape of pentagram have been specifically designed and fabricated for the purpose of assessing the efficacy and pract...
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Article
A Free-Space Measurement Technique of Terahertz Dielectric Properties
The free-space method for material dielectric characterization in the microwave band is extended to terahertz frequencies. By analyzing the advantages and disadvantages of the relative permittivity of the tran...