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  1. Article

    Open Access

    Histone acetyltransferase Kat2a regulates ferroptosis via enhancing Tfrc and Hmox1 expression in diabetic cardiomyopathy

    Diabetic cardiomyopathy (DCM) is a prevalent myocardial microvascular complication of the myocardium with a complex pathogenesis. Investigating the pathogenesis of DCM can significantly contribute to enhancing...

    Juan Zhen, **a Sheng, Tianlong Chen, Haitao Yu in Cell Death & Disease (2024)

  2. No Access

    Article

    Don’t Be So Dense: Sparse-to-Sparse GAN Training Without Sacrificing Performance

    This paper does not describe a novel method. Instead, it studies an incremental, yet must-know baseline given the recent progress in sparse neural network training and Generative Adversarial Networks (GANs). G...

    Shiwei Liu, Yuesong Tian, Tianlong Chen in International Journal of Computer Vision (2023)

  3. Article

    Open Access

    Two sequence- and two structure-based ML models have learned different aspects of protein biochemistry

    Deep learning models are seeing increased use as methods to predict mutational effects or allowed mutations in proteins. The models commonly used for these purposes include large language models (LLMs) and 3D ...

    Anastasiya V. Kulikova, Daniel J. Diaz, Tianlong Chen in Scientific Reports (2023)

  4. No Access

    Article

    A Novel Semi-Quantum Co-Signature Scheme Based on GHZ States and Four-Particle Cluster States

    The application of semi-quantum key distribution (SQKD) facilitates the development of semi-quantum technology, and semi-quantum signature (SQS) schemes emerged. However, there is no relatively complete securi...

    **ngqiang Zhao, Tianlong Chen in International Journal of Theoretical Physics (2023)

  5. Article

    Troubleshooting image segmentation models with human-in-the-loop

    Image segmentation lays the foundation for many high-stakes vision applications such as autonomous driving and medical image analysis. It is, therefore, of great importance to not only improve the accuracy of ...

    Haotao Wang, Tianlong Chen, Zhangyang Wang, Kede Ma in Machine Learning (2023)

  6. No Access

    Chapter and Conference Paper

    Enhancing Adversarial Training via Reweighting Optimization Trajectory

    Despite the fact that adversarial training has become the de facto method for improving the robustness of deep neural networks, it is well-known that vanilla adversarial training suffers from daunting robust o...

    Tian** Huang, Shiwei Liu, Tianlong Chen in Machine Learning and Knowledge Discovery i… (2023)

  7. No Access

    Chapter and Conference Paper

    Border Ownership, Category Selectivity and Beyond

    Object segmentation is a fundamental problem for both biological and machine vision systems. Recent advances in deep learning have allowed significant progress in terms of the ability of machine vision systems...

    Tianlong Chen, Xuemei Cheng, Thomas Tsao in Advances in Visual Computing (2022)

  8. No Access

    Chapter and Conference Paper

    DnA: Improving Few-Shot Transfer Learning with Low-Rank Decomposition and Alignment

    Self-supervised (SS) learning has achieved remarkable success in learning strong representation for in-domain few-shot and semi-supervised tasks. However, when transferring such representations to downstream t...

    Ziyu Jiang, Tianlong Chen, Xuxi Chen, Yu Cheng, Luowei Zhou in Computer Vision – ECCV 2022 (2022)

  9. No Access

    Chapter and Conference Paper

    Scalable Learning to Optimize: A Learned Optimizer Can Train Big Models

    Learning to optimize (L2O) has gained increasing attention since it demonstrates a promising path to automating and accelerating the optimization of complicated problems. Unlike manually crafted classical optimiz...

    Xuxi Chen, Tianlong Chen, Yu Cheng, Weizhu Chen in Computer Vision – ECCV 2022 (2022)

  10. No Access

    Chapter and Conference Paper

    Point Cloud Domain Adaptation via Masked Local 3D Structure Prediction

    The superiority of deep learning based point cloud representations relies on large-scale labeled datasets, while the annotation of point clouds is notoriously expensive. One of the most effective solutions is ...

    Hanxue Liang, Hehe Fan, Zhiwen Fan, Yi Wang, Tianlong Chen in Computer Vision – ECCV 2022 (2022)

  11. Article

    Open Access

    Efficient identification of multiple pathways: RNA-Seq analysis of livers from 56Fe ion irradiated mice

    mRNA interaction with other mRNAs and other signaling molecules determine different biological pathways and functions. Gene co-expression network analysis methods have been widely used to identify correlation ...

    Anna M. Nia, Tianlong Chen, Brooke L. Barnette, Kamil Khanipov in BMC Bioinformatics (2020)

  12. No Access

    Chapter and Conference Paper

    HALO: Hardware-Aware Learning to Optimize

    There has been an explosive demand for bringing machine learning (ML) powered intelligence into numerous Internet-of-Things (IoT) devices. However, the effectiveness of such intelligent functionality requires ...

    Chaojian Li, Tianlong Chen, Haoran You, Zhangyang Wang in Computer Vision – ECCV 2020 (2020)

  13. Article

    Open Access

    Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis

    Accessory sigma factors, which reprogram RNA polymerase to transcribe specific gene sets, activate bacterial adaptive responses to noxious environments. Here we reconstruct the complete sigma factor regulatory...

    Rinki Chauhan, Janani Ravi, Pratik Datta, Tianlong Chen in Nature Communications (2016)