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  1. Article

    Open Access

    PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins

    Neurodegenerative diseases are an enormous public health problem, affecting tens of millions of people worldwide. Nearly all of these diseases are characterized by oligomerization and fibrillization of neurona...

    Grant T. Corbett, Zemin Wang, Wei Hong, Marti Colom-Cadena… in Acta Neuropathologica (2020)

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    Article

    A comparative study of dietary curcumin, nanocurcumin, and other classical amyloid-binding dyes for labeling and imaging of amyloid plaques in brain tissue of 5×-familial Alzheimer’s disease mice

    Deposition of amyloid beta protein (Aβ) is a key component in the pathogenesis of Alzheimer’s disease (AD). As an anti-amyloid natural polyphenol, curcumin (Cur) has been used as a therapy for AD. Its fluoresc...

    Panchanan Maiti, Tia C. Hall, Leela Paladugu… in Histochemistry and Cell Biology (2016)