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    Adaptation of the ubiquitin-proteasome proteolytic pathway in cancer cachexia

    The ubiquitin-proteasome proteolytic pathway is of major importance in the breakdown of skeletal muscle proteins. The first step in this pathway is the covalent attachment of polyubiquitin chains to the target...

    Didier Attaix, Lydie Combaret, Thomas Tilignac in Molecular Biology Reports (1999)