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Article
Open AccessA self-supervised vision transformer to predict survival from histopathology in renal cell carcinoma
To develop and validate an interpretable deep learning model to predict overall and disease-specific survival (OS/DSS) in clear cell renal cell carcinoma (ccRCC).
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Article
Open AccessSystemic inflammatory biomarkers as predictive and prognostic factors in men with metastatic castration-refractory prostate cancer treated with docetaxel therapy: a comprehensive analysis in a German real-world cohort
Advances in therapy of metastatic castration-refractory prostate cancer (mCRPC) resulted in more therapeutic options and led to a higher need of predictive/prognostic biomarkers. Systemic inflammatory biomarke...
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Article
Open AccessChanges in neutrophile-to-lymphocyte ratio as predictive and prognostic biomarker in metastatic prostate cancer treated with taxane-based chemotherapy
To assess the predictive and prognostic value of changes in longitudinal neutrophile-to-lymphocyte (NLR) ratios in men receiving taxane-based chemotherapy for metastatic prostate cancer (PC).
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Article
Open AccessImmuntherapien in der Uroonkologie
Immun-Checkpoint-Inhibitoren (ICI) sind seit wenigen Jahren in der Uroonkologie zugelassen. Real-world-Erfahrung zu Nutzen und Risiken bei neuartigen Nebenwirkungen liegt kaum vor.
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Article
Open AccessCDKN2A as transcriptomic marker for muscle-invasive bladder cancer risk stratification and therapy decision-making
Deletions of the cell cycle control gene CDKN2A are described as progression markers of non-muscle invasive bladder cancer and to be associated with fibroblast growth factor 3 (FGFR3) mutations. The prognostic ro...
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Article
High PDL1 mRNA expression predicts better survival of stage pT1 non-muscle-invasive bladder cancer (NMIBC) patients
Checkpoint inhibition has emerged as new therapeutic option in muscle-invasive bladder cancer. The objective of the present study was to evaluate the prognostic role of PD1 and PDL1 expression in non-muscle-in...
