12 Result(s)

Article

CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude

Chimeric antigen receptor (CAR) T cell therapy is associated with high risk of adverse events. Glucocorticoids (GCs) are cornerstone in the management of high-grade cytokine release syndrome (CRS) and immune e...

Thomas Poiret, Sara Vikberg, Esther Schoutrop… in Journal of Translational Medicine (2024)

Article

Inducing expression of ICOS-L by oncolytic adenovirus to enhance tumor-specific bi-specific antibody efficacy

Intratumoral injection of oncolytic viruses (OVs) shows promise in immunotherapy: ONCOS-102, a genetically engineered OV that encodes Granulocyte–Macrophage Colony-Stimulating Factor (GM-CSF) demonstrated effi...

Neshat Saffarzadeh, Emelie Foord, Eoghan O’Leary… in Journal of Translational Medicine (2024)

Article

Linear epitope map** of the humoral response against SARS-CoV-2 in two independent African cohorts

Profiling of the antibody responses to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) proteins in African populations is scarce. Here, we performed a detailed IgM and IgG epitope map** study ag...

Inès Vigan-Womas, Jean-Louis Spadoni, Thomas Poiret, Fabien Taïeb… in Scientific Reports (2023)

Article

Epstein–Barr virus- and cytomegalovirus-specific immune response in patients with brain cancer

Patients with brain tumor or pancreatic cancer exhibit the poorest prognosis, while immune fitness and cellular immune exhaustion impacts their survival immensely. This work identifies differences in the immun...

Zhenjiang Liu, Thomas Poiret, Qingda Meng, Martin Rao… in Journal of Translational Medicine (2018)

Article

NY-ESO-1- and survivin-specific T-cell responses in the peripheral blood from patients with glioma

The prognosis for patients with glioblastoma is grim. Ex vivo expanded tumor-associated antigen (TAA)-reactive T-cells from patients with glioma may represent a viable source for anticancer-directed cellular t...

Zhenjiang Liu, Thomas Poiret, Oscar Persson… in Cancer Immunology, Immunotherapy (2018)

Article

IL-2, IL-15 and IL-21 expand T cells for targeted adoptive therapy

Zhenjiang Liu, Qingda Meng, Markus Maeurer… in Journal for ImmunoTherapy of Cancer (2015)

Article

Enhanced tumor-infiltrating lymphocytes (eTIL) for cellular therapy of patients with pancreatic cancer or glioblastoma

Qingda Meng, Zhenjiang Liu, Markus Maeurer… in Journal for ImmunoTherapy of Cancer (2015)

Article

Generation of tumor-infiltrating lymphocytes from pancreatic cancer lesions for cellular therapy

Qingda Meng, Elena B Rangelova, Liu zhenjiang… in Journal for ImmunoTherapy of Cancer (2014)

Article

A fast assay to gauge for TAA-reactive T cells in PBMCS from patients with pancreatic cancer

Elena B Rangelova, Qingda Meng, Liu zhenjiang… in Journal for ImmunoTherapy of Cancer (2014)

Article

Expression of TAAs in glioblastoma and expansion of anti-TAA -reactive T cells

Ernest Dodoo, Liu zhenjiang, Bartek Jiri… in Journal for ImmunoTherapy of Cancer (2014)

Article

Rapid expansion of TILs from patients with glioma and recognition of autologous tumor

Liu Zhenjiang, Qingda Meng, Oscar Persson… in Journal for ImmunoTherapy of Cancer (2014)

Article

Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults

Interleukin 7 (IL-7) signals via the IL-7 receptor (IL-7R) and drives homeostatic T-cell proliferation in patients after allogeneic hematopoietic stem cell transplantation (aHSCT).

Thomas Poiret, Lalit Rane, Mats Remberger, Birgitta Omazic… in BMC Immunology (2014)