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Article
Open AccessDetailed information gain and therapeutic impact of whole body computed tomography supplementary to conventional radiological diagnostics in blunt trauma emergency treatment: a consecutive trauma centre evaluation
The indication of whole body computed tomography (WBCT) in the emergency treatment of trauma is still under debate. We were interested in the detailed information gain obtained from WBCT following standardized...
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Article
Comparative analysis of MGAP, GAP, and RISC2 as predictors of patient outcome and emergency interventional need in emergency room treatment of the injured
Little is known about the capabilities of triage and risk scores to predict the outcomes of injured patients, other than mortality, or to determine the need for trauma center resources.
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Article
Short-term outcome following significant trauma: increasing age per se has only a relatively low impact
Ongoing demographic changes go hand in hand with an increasing number of elderly injured. Given the conflicting literature we wanted to know how much age per se, apart from other factors, actually explains the...
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Article
Open AccessStudy protocol medical rehabilitation after COVID-19 disease: an observational study with a comparison group with obstructive airway disease / Re_Co
Novel coronavirus disease 2019 (COVID-19) has been the subject of a numerous research projects over the past year. In cases with a severe disease course or threatening long-term impairment due to disease, the ...
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Article
Open AccessTranscriptome analysis reveals major transcriptional changes during regrowth after mowing of red clover (Trifolium pratense)
Red clover (Trifolium pratense) is globally used as a fodder plant due its high nutritional value and soil improving qualities. In response to mowing, red clover exhibits specific morphological traits to compensa...
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Article
Trauma center need: the American College of Surgeons’ definition in contrast to Swiss highly specialized medicine regulations—a Swiss trauma center perspective
According to the American College of Surgeons (ACS) recommendations, the benchmark for trauma center need (TCN) is an Injury Severity Score (ISS) > 15. In contrast, Swiss highly specialized medicine (HSM) regu...
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Article
Open AccessCharacterization of genes required for both Rpg1 and rpg4-mediated wheat stem rust resistance in barley
Puccinia graminis f. sp. tritici (Pgt) race TTKSK and its lineage pose a threat to barley production world-wide justifying the extensive efforts to identify, clone, and characterize the rpg4-mediated resistance l...
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Article
Genetic diversity of Aegilops L. species from Azerbaijan and Georgia using SSR markers
Five microsatellite (SSR) markers were used to evaluate the genetic diversity of six Aegilops species from Azerbaijan and Georgia. A total of 39 alleles were generated with an average of 7.8 alleles per primer. T...
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Article
One-year outcome following brain injury: a comparison of younger versus elderly major trauma patients
The increasing number of older trauma patients has provoked a debate on the need for subsequent rehabilitative therapy for the elderly. Our findings revealed a lack of detailed data on this topic so we became ...
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Article
Open AccessProspective evaluation of the Quality of Life after Brain Injury (QOLIBRI) score: minor differences in patients with major versus no or mild traumatic brain injury at one-year follow up
The Quality of Life after Brain Injury (QOLIBRI) score was developed to assess disease-specific health-related quality of life (HRQoL) after traumatic brain injury (TBI). So far, validation studies on the QOLI...
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Article
Genetic relationship of diploid wheat (Triticum spp.) species assessed by SSR markers
Genetic diversity of 139 accessions of diploid Triticum species including Triticum urartu, Triticum boeoticum and Triticum monococcum was studied using 11 SSR (simple sequence repeats) markers. A total of 111 all...
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Article
Open AccessSimple modification of trauma mechanism alarm criteria published for the TraumaNetwork DGU® may significantly improve overtriage – a cross sectional study
No consensus exists in the literature on the use of uniform emergency room trauma team activation criteria (ERTTAC). Today excessive over- or undertriage rates continue to be a challenge for most trauma centre...
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Chapter
Modular Pico-hydropower System for Remote Himalayan Villages
Remote, high-altitude villages in the Nepalese Himalayas belong to the poorest and most underdeveloped communities in Nepal, with many still years/decades away from access to electricity. It is common that fir...
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Article
Open AccessThe Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan
In Saccharomyces cerevisiae, deletion of large ribosomal subunit protein-encoding genes increases the replicative lifespan in a Gcn4-dependent manner. However, how Gcn4, a key transcriptional activator of amino a...
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Article
Open AccessThe selective antifungal activity of Drosophila melanogaster metchnikowin reflects the species-dependent inhibition of succinate–coenzyme Q reductase
Insect-derived antifungal peptides have a significant economic potential, particularly for the engineering of pathogen-resistant crops. However, the nonspecific antifungal activity of such peptides could resul...
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Article
Screening for osteoporosis following non-vertebral fractures in patients aged 50 and older independently of gender or level of trauma energy—a Swiss trauma center approach
Screening in a standardized manner for osteoporosis in non-vertebral fracture patients aged 50 and older independently of both gender and level of trauma energy yielded the indication for osteoporotic therapy ...
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Article
Morphology–elasticity relationships using decreasing fabric information of human trabecular bone from three major anatomical locations
With improving clinical CT scanning technology, the accuracy of CT-based finite element (FE) models of the human skeleton may be ameliorated by an enhanced description of apparent level bone mechanical propert...
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Chapter
Lichtsysteme
Bei der Gestaltung der Scheinwerfer für den neuen SL wurden auffälliges Tagund Nachtdesign mit der hohen Funktionalität des Intelligent Light Systems und des Adaptiven Fernlicht-Assistenten kombiniert. Realisi...
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Article
Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice
Constitutive activation of Signal Transducers and Activators of Transcription 3 (STAT3) is frequently detected in osteosarcoma, and hence, may serve as a therapeutic target. In order to target STAT3, we tested...
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Article
Ambient-ageing processes in amine self-assembled monolayers on microarray slides as studied by ToF-SIMS with principal component analysis, XPS, and NEXAFS spectroscopy
We investigated the ageing of amine-terminated self-assembled monolayers (amine-SAMs) on different silica substrates due to exposure to different ambient gases, pressures, and/or temperatures using time-of-fli...
